Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8857.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8857.t1
Gene ID Description PCC Relationship
g8857.t1AGAP004327-PA1positive
g1944.t1--0.99positive
g6270.t1BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER0.98positive
g6359.t1--0.98positive
g28014.t1SERINE-THREONINE PROTEIN KINASE0.98positive
g10452.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.98positive
g2094.t1--0.98positive
g6532.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 870.98positive
g8373.t1SIGNAL RECOGNITION PARTICLE 720.98positive
g9644.t1AXIN0.97positive
g15522.t1RIBONUCLEASE H2 SUBUNIT B0.97positive
g6450.t1DUAL SPECIFICITY PROTEIN PHOSPHATASE0.97positive
g35245.t1--0.97positive
g33269.t1--0.97positive
g11081.t1--0.97positive
g27203.t1WD40 REPEAT PROTEIN0.97positive
g29439.t1NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED0.97positive
g7052.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.97positive
g27260.t1SIDEROFLEXIN0.97positive
g11713.t1ADENOSYLHOMOCYSTEINASE0.97positive
g1971.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 510.97positive
g12395.t1LYSOSOMAL ACID LIPASE-RELATED0.97positive
g13385.t1SERINE/THREONINE-PROTEIN KINASE RIO10.96positive
g15643.t1TUBULIN0.96positive
g4778.t1CELL DIVISION PROTEIN KINASE0.96positive
g23802.t1--0.96positive
g2803.t1IP01015P-RELATED0.96positive
g22283.t1--0.96positive
g7841.t1YEAST SPT2-RELATED0.96positive
g15786.t1ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN0.96positive
g27894.t1HISTIDINE TRIAD HIT PROTEIN0.96positive
g7487.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 30.96positive
g29451.t1--0.96positive
g704.t1METHYL-CPG BINDING PROTEIN, MBD0.96positive
g10627.t1RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 10.95positive
g9780.t1--0.95positive
g15492.t1DDRGK DOMAIN-CONTAINING PROTEIN 10.95positive
g32453.t1--0.95positive
g10814.t1DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED0.94positive
g17022.t1MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L490.94positive
g9762.t1ALDEHYDE DEHYDROGENASE-RELATED0.94positive
g33500.t1--0.94positive
g2792.t1HOMEOBOX PROTEIN NKX0.94positive
g27137.t1--0.93positive
g3857.t1ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 352 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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