Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8895.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8895.t1
Gene ID Description PCC Relationship
g8895.t1CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS1positive
g2446.t1--0.89positive
g3207.t1--0.89positive
g3742.t1PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.88positive
g308.t1CENTROSOMAL PROTEIN KIZUNA0.87positive
g8055.t1BETA TRANSDUCIN-RELATED PROTEIN0.87positive
g18161.t1VILLIN0.86positive
g20116.t1UNCHARACTERIZED0.85positive
g23704.t1SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED0.85positive
g16897.t1RAD25/XP-B DNA REPAIR HELICASE0.85positive
g7922.t1RP42 RELATED0.85positive
g8886.t1AMINOPEPTIDASE O0.85positive
g27171.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.84positive
g4966.t1PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED0.84positive
g9920.t1--0.84positive
g23458.t1--0.84positive
g17456.t1BCS1 AAA-TYPE ATPASE0.83positive
g27813.t1E3 UBIQUITIN-PROTEIN LIGASE TRIM370.83positive
g20115.t1UNCHARACTERIZED0.83positive
g6221.t1CENTROSOMAL PROTEIN OF 131 KDA0.83positive
g13187.t1CENTAURIN/ARF0.83positive
g29051.t1PERICENTRIOLAR MATERIAL 1-RELATED0.83positive
g1399.t1TGF-BETA FAMILY0.82positive
g30567.t1BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED0.82positive
g3898.t1MDM2-BINDING PROTEIN0.82positive
g12324.t1DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL0.81positive
g12630.t1--0.81positive
g11685.t1KU AUTOANTIGEN DNA HELICASE0.80positive
g31117.t1ATP-DEPENDENT RNA HELICASE0.77positive
g11144.t1DRAB11-RELATED0.74positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 113 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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