Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g89.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g89.t1
Gene ID Description PCC Relationship
g89.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED1positive
g31652.t1--0.97positive
g16689.t1RETROTRANSPOSON0.94positive
g31947.t1ENDONUCLEASE-RELATED0.91positive
g16739.t1--0.89positive
g7144.t1--0.87positive
g15966.t1PROTEIN CBG238060.86positive
g11148.t1--0.84positive
g10263.t1--0.83positive
g33541.t1--0.82positive
g16252.t1TYROSINE-PROTEIN KINASE RECEPTOR0.80positive
g4216.t1--0.78positive
g5848.t1--0.77positive
g24226.t1--0.77positive
g26380.t1UNCHARACTERIZED0.76positive
g28536.t1PROTEIN CBG266940.76positive
g14778.t1--0.72positive
g24220.t1--0.71positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 58 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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