Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8971.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8971.t1
Gene ID Description PCC Relationship
g8971.t1--1positive
g7350.t1PERICENTRIN-LIKE PROTEIN, ISOFORM F0.98positive
g13101.t1CDC73 DOMAIN PROTEIN0.97positive
g27061.t1RAB GDP-DISSOCIATION INHIBITOR0.97positive
g6623.t1ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 20.97positive
g10191.t1ZINC FINGER PROTEIN 2940.97positive
g23603.t1SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO0.97positive
g14500.t1PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE0.96positive
g24953.t1--0.96positive
g16765.t1PHOSPHATIDYLCHOLINE TRANSFER PROTEIN0.96positive
g22809.t1CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS0.96positive
g35490.t1DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED0.96positive
g6191.t1SERINE/THREONINE-PROTEIN KINASE0.96positive
g28018.t1ALPHA-MANNOSIDASE0.96positive
g1428.t1BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR0.96positive
g28145.t1SPECKLE-TYPE POZ PROTEIN0.96positive
g12287.t1NETRIN/LAMININ-RELATED0.96positive
g3212.t1LONG-CHAIN-FATTY-ACID--COA LIGASE0.95positive
g11655.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 120.95positive
g4039.t1AP-5 COMPLEX SUBUNIT ZETA-10.95positive
g24339.t1PRE-MRNA SPLICING FACTOR0.95positive
g27161.t1ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE0.95positive
g12023.t1ZINC FINGER PROTEIN-RELATED0.95positive
g16285.t1GUANYL-NUCLEOTIDE EXCHANGE FACTOR0.95positive
g23507.t1LEUCINE RICH REPEAT FAMILY PROTEIN0.95positive
g17701.t1INOSITOL 5-PHOSPHATASE0.95positive
g35047.t1GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN0.94positive
g35508.t1MYOTONIC DYSTROPHY S/T KINASE-RELATED0.94positive
g21082.t1OVOCHYMASE-RELATED0.94positive
g13338.t1HERMANSKY-PUDLAK SYNDROME 3 PROTEIN0.94positive
g22787.t1ROTATIN0.94positive
g30044.t1ARGININE-TRNA-PROTEIN TRANSFERASE 10.94positive
g27968.t1RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS0.93positive
g12046.t1PAPILLOMAVIRUS REGULATORY FACTOR PRF-10.93positive
g17387.t1--0.93positive
g34407.t1KELCH PROTEIN0.92positive
g7615.t1--0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 183 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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