Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8982.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8982.t1
Gene ID Description PCC Relationship
g8982.t1TETRATRICOPEPTIDE REPEAT PROTEIN 41positive
g31313.t1ACTIN0.89positive
g6675.t1LOQUACIOUS, ISOFORM B0.89positive
g10495.t1IMPORTIN BETA0.88positive
g28181.t1SODIUM-DEPENDENT GLUCOSE TRANSPORTER 10.87positive
g30735.t1LEUCYL-TRNA SYNTHETASE0.87positive
g28409.t1F-BOX ONLY PROTEIN 30.87positive
g31091.t1PERIODIC TRYPTOPHAN PROTEIN 10.87positive
g19260.t1GEO13361P1-RELATED0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 17 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP