Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g9085.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g9085.t1
Gene ID Description PCC Relationship
g9085.t1--1positive
g12698.t1TOPOISOMERASE II-ASSOCIATED PROTEIN PAT10.94positive
g31506.t1CENTROSOMAL PROTEIN OF 162 KDA0.94positive
g18793.t1MULTIVESICULAR BODY SUBUNIT 12A0.94positive
g24302.t1--0.93positive
g27831.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.93positive
g2997.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.92positive
g27562.t1E3 UBIQUITIN-PROTEIN LIGASE TRIP120.92positive
g2565.t1RIBOSOME BINDING PROTEIN-10.92positive
g11089.t1OS06G0237300 PROTEIN0.92positive
g12549.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED0.92positive
g9084.t1CHROMOSOME TRANSMISSION FIDELITY FACTOR 180.91positive
g7417.t1--0.91positive
g656.t1--0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 37 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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