Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g9273.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g9273.t1
Gene ID Description PCC Relationship
g9273.t1TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED1positive
g7552.t1RHO-TYPE GTPASE ACTIVATING PROTEIN0.96positive
g12287.t1NETRIN/LAMININ-RELATED0.96positive
g1837.t1ANOCTAMIN0.95positive
g18266.t1TRANSCRIPTION ELONGATION FACTOR SPT60.95positive
g30314.t1--0.95positive
g19185.t1TNF RECEPTOR ASSOCIATED FACTOR0.95positive
g10812.t1PERIOSTIN-RELATED0.95positive
g3316.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED0.95positive
g10375.t1ZGC:1951700.95positive
g9772.t1COLLAGEN ALPHA0.94positive
g24367.t1--0.94positive
g2067.t1COLLAGEN ALPHA0.94positive
g9776.t1COLLAGEN ALPHA0.94positive
g16730.t1PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC10.94positive
g6524.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.94positive
g32416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1580.94positive
g7540.t1--0.94positive
g13790.t1ANGIOTENSIN-CONVERTING ENZYME0.93positive
g12968.t1--0.93positive
g27860.t1CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA0.93positive
g17188.t1UBIQUITINATION FACTOR E40.93positive
g12970.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.93positive
g6410.t1--0.93positive
g10302.t1SODIUM/DICARBOXYLATE SYMPORTER-RELATED0.93positive
g212.t1RETROTRANSPOSON0.92positive
g12675.t1N-ACETYLGALACTOSAMINYLTRANSFERASE0.92positive
g9445.t1EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN0.91positive
g19663.t1SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED0.90positive
g17445.t1RETROTRANSPOSON0.85positive
g29616.t1--0.78positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 120 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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