Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g9548.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g9548.t1
Gene ID Description PCC Relationship
g9548.t1TUBBY-RELATED1positive
g20916.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.98positive
g10847.t1UNNAMED PRODUCT0.98positive
g18298.t1--0.98positive
g15843.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.97positive
g121.t1TRANSCRIPTION FACTOR ONECUT0.97positive
g16373.t1RAN BINDING PROTEIN 9-RELATED0.97positive
g16960.t1--0.97positive
g11629.t1KNIRPS-RELATED PROTEIN-RELATED0.97positive
g19449.t1--0.97positive
g5620.t1TRANSCRIPTION INTERMEDIARY FACTOR0.97positive
g35727.t1UNCHARACTERIZED0.97positive
g35419.t1--0.97positive
g18457.t1KELCH PROTEIN0.96positive
g6093.t1FAST LEU-RICH DOMAIN-CONTAINING0.96positive
g18351.t1TTC17 PROTEIN0.96positive
g12759.t1SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG0.96positive
g3080.t1POLYCYSTIN FAMILY MEMBER0.96positive
g13575.t1FORKHEAD BOX PROTEIN J2 FAMILY MEMBER0.96positive
g16533.t1MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 130.96positive
g8043.t1ZINC FINGER PROTEIN0.96positive
g11552.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.96positive
g7886.t1MYELIN TRANSCRIPTION FACTOR 1-RELATED0.96positive
g29834.t1HAMARTIN0.96positive
g27737.t1DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED0.96positive
g6288.t1GUANYL-NUCLEOTIDE EXCHANGE FACTOR0.96positive
g2587.t1P140CAP/SNIP-RELATED0.95positive
g4202.t1ANAPHASE-PROMOTING COMPLEX SUBUNIT 20.95positive
g16369.t1RAN BINDING PROTEIN 9-RELATED0.95positive
g14880.t1DDB1- AND CUL4-ASSOCIATED FACTOR 150.95positive
g7257.t1RING FINGER PROTEIN 1270.95positive
g6838.t1SERINE-THREONINE PROTEIN KINASE0.95positive
g26021.t1FORKHEAD BOX PROTEIN J2 FAMILY MEMBER0.95positive
g335.t1VACUOLAR PROTEIN SORTING 540.95positive
g34387.t1--0.95positive
g22911.t1LD33804P0.95positive
g16961.t1ABC TRANSPORTER G FAMILY MEMBER 280.95positive
g23936.t1POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED0.95positive
g21236.t1PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER0.94positive
g8884.t1PROBABLE MEMBRANE PROTEIN DUF221-RELATED0.94positive
g3388.t1--0.94positive
g34907.t1RASSF0.94positive
g769.t1GLYCOGENIN SUBFAMILY MEMBER0.94positive
g22912.t1LD33804P0.94positive
g15870.t1PROTEIN TORNADO 10.94positive
g15176.t1INSULIN RECEPTOR SUBSTRATE0.92positive
g19717.t1LD33804P0.92positive
g16218.t1DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED0.92positive
g35161.t1UNCHARACTERIZED0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 321 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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