Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g9748.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g9748.t1
Gene ID Description PCC Relationship
g9748.t1TYROSINE-PROTEIN KINASE RECEPTOR1positive
g23003.t1CYTOCHROME P450 FAMILY 30.99positive
g1440.t1TRANSLATIONAL ACTIVATOR GCN1-RELATED0.98positive
g94.t1DNA-BINDING PROTEIN INHIBITOR0.98positive
g33163.t1--0.98positive
g11498.t1SODIUM/CHLORIDE DEPENDENT TRANSPORTER0.98positive
g23073.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.97positive
g3871.t1MYOTROPHIN0.97positive
g17725.t1UNCHARACTERIZED0.97positive
g4937.t1--0.97positive
g21216.t1FRINGE-RELATED0.97positive
g26959.t1GUANYL-NUCLEOTIDE EXCHANGE FACTOR0.97positive
g27682.t1UNCHARACTERIZED0.97positive
g16498.t1TFIIF-ALPHA0.97positive
g8073.t1PR DOMAIN ZINC FINGER PROTEIN0.97positive
g1311.t1CHONDROITIN SYNTHASE0.97positive
g13399.t1FATTY-ACID AMIDE HYDROLASE0.97positive
g3193.t1FRIZZLED0.96positive
g8952.t1T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN0.96positive
g601.t1TETRATRICOPEPTIDE REPEAT PROTEIN 130.96positive
g17808.t1PROPERDIN0.96positive
g10812.t1PERIOSTIN-RELATED0.96positive
g28070.t1NXPE FAMILY MEMBER0.96positive
g33775.t1CARBOHYDRATE SULFOTRANSFERASE0.96positive
g1112.t1SUGAR-1-PHOSPHATE GUANYL TRANSFERASE0.96positive
g13908.t1--0.96positive
g6594.t1ALKALINE PHOSPHATASE0.96positive
g8975.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.96positive
g13790.t1ANGIOTENSIN-CONVERTING ENZYME0.95positive
g122.t1NATRIURETIC PEPTIDE RECEPTOR 3-RELATED0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 162 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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