Gene detail

Detailed information of ANN05050-RA in Nanomia septata

Genomic Location: chr2:64177174...64177869
NR annotation: XP_012558685.2, thiopurine S-methyltransferase [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P51580	Thiopurine S-methyltransferase OS=Homo sapiens OX=9606 GN=TPMT PE=1 SV=1
Q3BCR8	Thiopurine S-methyltransferase OS=Pan troglodytes OX=9598 GN=TPMT PE=2 SV=1
Q3BCR3	Thiopurine S-methyltransferase OS=Gorilla gorilla gorilla OX=9595 GN=TPMT PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF05724	TPMT	Thiopurine S-methyltransferase (TPMT)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029063	Homologous_superfamily	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Interproscan
IPR008854	Family	TPMT family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10259	THIOPURINE S-METHYLTRANSFERASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008757	Molecular Function	S-adenosylmethionine-dependent methyltransferase activity	Interproscan
GO:0008119	Molecular Function	thiopurine S-methyltransferase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00569	TPMT, tpmT; thiopurine S-methyltransferase	EC:2.1.1.67	Drug metabolism - other enzymes	ko00983	deepkoala