Detailed information of ANN05587-RA in Nanomia septata

Genomic Location: chr2:95468653...95470419
NR annotation: XP_047125773.1, NAD-dependent protein deacetylase sirtuin-1 isoform X1 [Hydra vulgaris]


 Gene Structure
More details in Jbrowse  Sequence
CDS
Transcript
Protein
 Uniprot
Uniprot termDescription
Q923E4NAD-dependent protein deacetylase sirtuin-1 OS=Mus musculus OX=10090 GN=Sirt1 PE=1 SV=2
A0A0G2JZ79NAD-dependent protein deacetylase sirtuin-1 OS=Rattus norvegicus OX=10116 GN=Sirt1 PE=3 SV=2
Q96EB6NAD-dependent protein deacetylase sirtuin-1 OS=Homo sapiens OX=9606 GN=SIRT1 PE=1 SV=2

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02146SIR2Sir2 familyFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR003000FamilySirtuin familyInterproscan
IPR050134FamilyNAD-dependent sirtuin protein deacylasesInterproscan
IPR026591Homologous_superfamilySirtuin, catalytic core small domain superfamilyInterproscan
IPR029035Homologous_superfamilyDHS-like NAD/FAD-binding domain superfamilyInterproscan
IPR026590DomainSirtuin family, catalytic core domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11085NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATEDInterproscan

 Gene Ontology
GO termsCategoryDescriptionSource
GO:0070403Molecular FunctionNAD+ bindingInterproscan
GO:0002039Molecular Functionp53 bindingInterproscan
GO:0003714Molecular Functiontranscription corepressor activityInterproscan
GO:0005634Cellular ComponentnucleusInterproscan
GO:0005637Cellular Componentnuclear inner membraneInterproscan
GO:0005654Cellular ComponentnucleoplasmInterproscan
GO:0017136Molecular Functionhistone deacetylase activity, NAD-dependentInterproscan
GO:0033553Cellular ComponentrDNA heterochromatinInterproscan
GO:0045892Biological Processnegative regulation of DNA-templated transcriptionInterproscan
GO:0070932Biological Processobsolete histone H3 deacetylationInterproscan

 KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K11411SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1EC:2.3.1.286
Mitochondrial biogenesisko03029deepkoala

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