Gene detail

Detailed information of ANN11892-RA in Montipora grisea

Genomic Location: Scaffold_5__1_contigs__length_50351834:35358288...35414521
NR annotation: XP_044184195.1, LOW QUALITY PROTEIN: AP-2 complex subunit alpha-2-like [Acropora millepora]
Species Montipora grisea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ANN11892-RA

ATGCCTGCCGTAAAGGGAGAAGGAATGCGCGGCTTAGCCGTGTTTATTTCCGACATTCGGAACTGCAAGTCGAAAGAGGCAGAAATGAAAAGAATCAACAAGGAACTCGCAAATATTAGAAATAAATTCAAAGGTGATAAACAGTTAGACGGTTATCAAAAGAAAAAATACGTGTGCAAGTTGCTGTTTATTTTCCTTCTGGGTCATGACATCGACTTTGGTCACATGGAAGCAGTAAATCTGCTCTCGTCGAACAAATACACAGAAAAGCAAATTGGCTACCTCTTTATATCTGTCTTGGTTAGTGCAAACAGTGAACTGATCAAGCTGATTCTTCAAAGTATCAAGAATGACTTGTCCAGTCGCAACCCCATCAATGTCTGTTTAGCACTCCAGTGCATAGCAAATATCGGCAATGATGAGATGGTTGAAGCAGTGGGAAAAGAAGTACCAAAGCTGTTAGTCTCTCCAGATACAAATGATAGCGTCAAACAGTGTGCAGCCCTTTGTGTGTTGAAGCTCTTTAGGCTCAAAACAGACATCTTGCCTCCTGGAGAATGGACATCAAGAATAGTACAGCTCTTAAATGACAAGCACTTGGGTGTGGTCACCTCTGCCGCTAGTCTAATTCAAGGTGTTGTCCATCACTATGCTGATGATTACAAAGGATGTGTCCAACTAGCAGTGTCAAGACTAAGTAGGATTGTGACATCATCATACACAGACCTCCAAGATTACACTTATTACTTTGTTCCAGCACCATGGCTGTGTGTCAAACTGCTTAAACTTTTGCAGCTGTATCCTTCACCAGATGATCCAGCCATCCATGCACGATTAAATGAATGTCTTGAAACCATTTTGAACAAAGCACAGGAGCCACCAAAATCCAAGAAAGTCCAGCACTCAAATGCAAGAAATGCTGTACTTTTTGAAGCTATAAACCAGATTATTCACATGGATAGTGAACAAAGTTTGCTGATCAGAGGGTGTAACCAGCTGGGTCAGTTTTTGACACACAGGGAAACCAACCTTAGATATCTTGCTTTAGAAGGTCTTTGTTTAATGTCCAACTCCGAGTTCTCAGCTGATGCTGTCAGAAAACATCAAGAGACTGTTGTTTCAGCACTGAAGACTGAACGTGATGTCAGTGTGCGCCAGAGAGCAGTTGATCTTCTTTATGCTATGTGTGATAAGAACAACGCTGAAGAGATAGTGTCAGAAATGTTGACGTACTTGGAAACAGCTGATTATTCCATCAAGGAGGAAATGGTACTAAAAGTTGCAATACTTGCTGAGAAGTTTGCCACTGACTACTCCTGGTACATGGACACCATCCTAACACTAATCAGAAATGCAGGGGATTATGTCAGCGAAGAAGTATGGTATCGTGTGATCCAGATTGTCATAAACAGGGATGATATCCAAGGCTATGCAGCTAAGACAGTGTTTGAGGCCCTGCAGTCACCATCGTGCCATGAGAATATGGTGAAAGTCGGTGGTTACATCTTAGGAGAGTTTGGAAATCTTATCGCTGGTGATCCACGCTCGAGTCCAATGGTCCAGTTCCAGCTTCTTCATAGCAAGTTCCCATTGTGTTGTTCTTCAACAAGAGGTTTACTGATGTCAACATATGTCAAGTTTATTAACCTTTTCCCAGAGATCAAGGGACACATTCAAGAGATTTTGCGAAGTGATTCTAACCTCAAGAATTCGGATGCAGAAATTCAGCAGAGAGCTTTGGAATACTTGAAACTTAGTACTGTTGCATCCCCTGATGTATTGGCTACTGTGCTTGAAGAAATGCCACCTTTTCCAGAAAGGGAGTCATCCATCTTGGCTAAGTTGAAGAAGAAAAAACAAGAGAAGACTGGAATAGTCGAGAAGGAAGAAAAGGCTGAACCTGCTGAAAAACCAACAACAAATGGACAAGTTCCAGTAGCAAATGAAGTGCCTGTGCATCTCCCTCCTTCAAATCCTGCATTGCAAGCAGATCTCATTGGCACAGGAAATGCTCCTTTCGTAAACAACTTTGCAGCTTCAGATACTGCGGGTGGAGGGCTTCTTGTCGACGTGTTTGACATCCCAGCAGCAACACCAGCGCCAGTGATAGGGGGTATTCCTACCATTAACCCTGGAACAGAGGAGAATCTTAAAAAATTTGTGTTCAAAAACACTGGCGTTTTGTTTGAAAACGACATTCTCCAAGTTGGAATAAAATCAGAATTTAGCGACACAAAGGGAGCTATTGGTATATTTTATGGCAACAAGACGTCTTCACAATTTGTTAATTTCTCCTCCACTGTTCACAGTCCTGATGATCTCAATACTCATATCCTTTTACATGCCAGATCAACCTCGTTTCCTGTCTCTATCTTCTCTGCCTCTTTTATGAAACAGATGATTAACGTAGAGTGCATCATGGAATTCAATGCTCATCCAATCGTAGACCTTCAGTTCAGTGTGAACGGCATGGGCCAAAGAATTGCTCTTCCTTTGCCCGTGTTTGCGTCCAAGTTTTTTGCACCCACGGACATGAATTCACAGGACTTCTTTTCTAGATGGAAACAATTAGGAAATCCTGGTCAAGAATGCCAGCAGATCTTTAAAGCTAAGTTTCCCATCGATACAGAAACGGTTAAAGCAAAGCTTGTCGGTTTTGGGATGTCCTTGCTCCAGAGTGTCGATCCTAATCCAGAGAATTTTGTTTGTGCTGGTATAATCAAGGCGCGAACAGTTCAAATTGGAACACTGTTGCGATTGGAACCTAACAGACAAGCACAGATGTTCAGATTGACAATACGAAGTTCAAGGGCTGACGTCGCCAAATACCTTGTAGATATATTGATTGACCACTGCATGAAACGTGTTTTCTGGAGTACATTAGTGGACATTGAAATATTTGTTGCTTTACAACGAATTTTGACAGCATTCAGCTTTGGTCGACCTAAATCCATGTTTGAAATGGCGGAGAAGTTTAAAACGCGAGGAGATCAAGAGGAACGCGATCTGAAAAGATTTTTAAAATTTCTGTCCTTCAAGGCTGTACAAGTCATTGTTCAGTCCCGTCTTGGTGAGAAGATTCATACAAAGTCGAAGCCTAATTCTATGGGTCAAGACTGGTTCAATCTTGCTATAAATGATCATCCGGATGTTGCTGCTGAAGCAAAGAAAGTCACAAGTGGAAGGCTTCCTTCCAAGGAAAGTCCATTGTGTGTTGAGATATCTCTGAAAACCAGTGAGGGTGAATCCATGGTGCTAGAGACATGGTGCCTTGGCATAAATGACCGTGTTGATTTAAATGCAAAAGTGACATACGCAGTTTACAACAGAATCGGAATGCTACTCAAATCTCTTGTGTCAGTCACAAGAGTGACACCAGCCTATCAGCTGTCACGAAAGCAGGGGACAGACTTCATGATGTGCTACAAGGTATATTTTGGAGAAAGTTTAAGAGTTGGTTCGATTGGTACGCCTGTGGGATCCATTACATTGTCTGCAGCATACAGAACAAAACTGACTTTACCAGAAAGACCTCAACTGGTAAAGCAGAGTCATCACTTGAAGTCTGAGCCGGCAGGTGTGTCATGTGATCAACTGGATGGTGTTTTGCAGTGTATGCCAGGTGCCTTTGACTTGACAGCTGAAGCAAGGCATCATATTGCTGAGCAGATAGCTAGTGCAACTGAAACGGAAGTGACCCAGTCCTCCACAGTGTCCTCAAATACCCCGCCATCCTCAACTCACAGACTGAGTTCAACCTCTCCACCCCCCTTTATCAGACGATTGTCTCAGGAAAACGGCCTCATTGGAAAACAGGAGATTGAAAGGGAAAGGTCAACAACTTCTCCTAAGGTGATAAATAGTAAGCAAGTACGAACGAAGGTGGCGTTTGTCAGTGGACCGGAATCTCCTCAAAAGCCCATGTTTACAAACTTGTCCTCAACTCCGCCGTTTGCTTCGCTATTGCGGCACGAAAATGACAAACCAATCGACTTACCCTCAGATGACAATCGGTTGAATCCGCCCTCTACACTCAACAGAAGGGACAGCTCATCAGATACAACAGAGAGAAGACCGCCAACATCTCAGGCAGTTCTACAAGCCCCCAGTCAGCAAGGGTGGGACGATGACTTTGTTATGGTTGAATTGAAACCGGCCTTTGCATCGAATTCAGGGACTTCCACTGGGGATCTTGGTAGCTTTTTTCGAGAGTGTCAAACGGCTCCTCCTCTGAGCCTTTTCCAGGATACTGAAATAGCAGCCGTGGATAACATCATGGAGCACTTGGATGGAGAACTTTGTGGTTTCCGACGGAACGCTTCCAAATTTGATGAACTCTTAGCAGATCTGCAACAGACGTGA

Transcript

ANN11892-RA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P18484	AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Ap2a2 PE=1 SV=3
Q0VCK5	AP-2 complex subunit alpha-2 OS=Bos taurus OX=9913 GN=AP2A2 PE=1 SV=1
P17427	AP-2 complex subunit alpha-2 OS=Mus musculus OX=10090 GN=Ap2a2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003616 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02296 all species →	Alpha_adaptin_C	Alpha adaptin AP2, C-terminal domain	Family	Interproscan
PF01602 all species →	Adaptin_N	Adaptin N terminal region	Repeat	Interproscan
PF02883 all species →	Alpha_adaptinC2	Adaptin C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003164 all species →	Domain	Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR012295 all species →	Homologous_superfamily	TBP domain superfamily	Interproscan
IPR002553 all species →	Domain	Clathrin/coatomer adaptor, adaptin-like, N-terminal	Interproscan
IPR036570 all species →	Homologous_superfamily	HORMA domain superfamily	Interproscan
IPR008152 all species →	Domain	Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR013041 all species →	Homologous_superfamily	Clathrin adaptor, appendage, Ig-like subdomain superfamily	Interproscan
IPR009028 all species →	Homologous_superfamily	Coatomer/calthrin adaptor appendage, C-terminal subdomain	Interproscan
IPR050840 all species →	Family	Adaptor Complexes Large Subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22780 all species →	ADAPTIN, ALPHA/GAMMA/EPSILON	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006886 all species →	Biological Process	intracellular protein transport	Interproscan
GO:0016192 all species →	Biological Process	vesicle-mediated transport	Interproscan
GO:0030131 all species →	Cellular Component	clathrin adaptor complex	Interproscan
GO:0030117 all species →	Cellular Component	membrane coat	Interproscan
GO:0030122 all species →	Cellular Component	AP-2 adaptor complex	Interproscan
GO:0035615 all species →	Molecular Function	clathrin adaptor activity	Interproscan
GO:0072583 all species →	Biological Process	clathrin-dependent endocytosis	Interproscan
GO:0140312 all species →	Molecular Function	cargo adaptor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11824	AP2A; AP-2 complex subunit alpha	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →