Genomic Location: chr5:195811291...195826485
NR annotation: XP_047125034.1, ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [Hydra vulgaris]
| CDS | |||||
| ANN13864-RA | |||||
| Transcript |
| ANN13864-RA |
| Protein |
| ANN13864-RA |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| P40818 | Ubiquitin carboxyl-terminal hydrolase 8 OS=Homo sapiens OX=9606 GN=USP8 PE=1 SV=1 | ||||
| Q80U87 | Ubiquitin carboxyl-terminal hydrolase 8 OS=Mus musculus OX=10090 GN=Usp8 PE=1 SV=2 | ||||
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 OS=Homo sapiens OX=9606 GN=USP2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | DUB|USP|USP |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00397 | WW | WW domain | Domain | Interproscan |
| PF00443 | UCH | Ubiquitin carboxyl-terminal hydrolase | Family | Interproscan |
| PF08969 | USP8_dimer | USP8 dimerisation domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001763 | Domain | Rhodanese-like domain | Interproscan |
| IPR001202 | Domain | WW domain | Interproscan |
| IPR038765 | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR050185 | Family | Ubiquitin carboxyl-terminal hydrolase | Interproscan |
| IPR036873 | Homologous_superfamily | Rhodanese-like domain superfamily | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR001394 | Domain | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Interproscan |
| IPR015063 | Domain | USP8 dimerisation domain | Interproscan |
| IPR018200 | Conserved_site | Ubiquitin specific protease, conserved site | Interproscan |
| IPR028889 | Domain | Ubiquitin specific protease domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21646 | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004843 | Molecular Function | cysteine-type deubiquitinase activity | Interproscan |
| GO:0016579 | Biological Process | protein deubiquitination | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11839 | USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 | EC:3.4.19.12 | Ubiquitin system | ko04121 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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