Genomic Location: chr3:83474590...83477781
NR annotation: XP_002159249.1, disintegrin and metalloproteinase domain-containing protein 17 [Hydra vulgaris]
| CDS | |||||
| ANN15283-RA | |||||
| Transcript |
| ANN15283-RA |
| Protein |
| ANN15283-RA |
| Uniprot term | Description |
|---|---|
| Q9VAC5 | ADAM 17-like protease OS=Drosophila melanogaster OX=7227 GN=Tace PE=2 SV=2 |
| P78536 | Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ADAM17 PE=1 SV=1 |
| Q9Z1K9 | Disintegrin and metalloproteinase domain-containing protein 17 OS=Rattus norvegicus OX=10116 GN=Adam17 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13574 | Reprolysin_2 | Metallo-peptidase family M12B Reprolysin-like | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001762 | Domain | Disintegrin domain | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR036436 | Homologous_superfamily | Disintegrin domain superfamily | Interproscan |
| IPR001590 | Domain | Peptidase M12B, ADAM/reprolysin | Interproscan |
| IPR051489 | Family | Disintegrin and Metalloproteinase Domain-Containing | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45702 | ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006509 | Biological Process | membrane protein ectodomain proteolysis | Interproscan |
| GO:0007219 | Biological Process | Notch signaling pathway | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K06059 | ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 | EC:3.4.24.86 | CD molecules | ko04090 | deepkoala |