Gene detail

Detailed information of ANN16233-RA in Nanomia septata

Genomic Location: chr3:138168789...138169793
NR annotation: XP_002158608.3, procathepsin L [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q26636	Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 SV=1
A0A1S4F2V5	Cathepsin L-like peptidase OS=Aedes aegypti OX=7159 PE=1 SV=1
Q9GL24	Procathepsin L OS=Canis lupus familiaris OX=9615 GN=CTSL PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00112	Peptidase_C1	Papain family cysteine protease	Domain	Interproscan
PF08246	Inhibitor_I29	Cathepsin propeptide inhibitor domain (I29)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR039417	Domain	Papain-like cysteine endopeptidase	Interproscan
IPR013128	Family	Peptidase C1A	Interproscan
IPR000668	Domain	Peptidase C1A, papain C-terminal	Interproscan
IPR025661	Active_site	Cysteine peptidase, asparagine active site	Interproscan
IPR013201	Domain	Cathepsin propeptide inhibitor domain (I29)	Interproscan
IPR038765	Homologous_superfamily	Papain-like cysteine peptidase superfamily	Interproscan
IPR025660	Active_site	Cysteine peptidase, histidine active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12411	CYSTEINE PROTEASE FAMILY C1-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004197	Molecular Function	cysteine-type endopeptidase activity	Interproscan
GO:0005615	Cellular Component	extracellular space	Interproscan
GO:0005764	Cellular Component	lysosome	Interproscan
GO:0006955	Biological Process	immune response	Interproscan
GO:0008234	Molecular Function	cysteine-type peptidase activity	Interproscan
GO:0008656	Molecular Function	cysteine-type endopeptidase activator activity involved in apoptotic process	Interproscan
GO:0010952	Biological Process	positive regulation of peptidase activity	Interproscan
GO:0051603	Biological Process	proteolysis involved in protein catabolic process	Interproscan
GO:2001235	Biological Process	positive regulation of apoptotic signaling pathway	Interproscan
GO:0006508	Biological Process	proteolysis	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01365	CTSL; cathepsin L	EC:3.4.22.15	Glycosylphosphatidylinositol (GPI)-anchored proteins	ko00537	deepkoala