Gene detail

Detailed information of ANN16447-RA in Nanomia septata

Genomic Location: chr3:150924763...150943458
NR annotation: XP_002155458.1, transmembrane prolyl 4-hydroxylase isoform X1 [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q8BG58	Transmembrane prolyl 4-hydroxylase OS=Mus musculus OX=10090 GN=P4htm PE=1 SV=1
Q9NXG6	Transmembrane prolyl 4-hydroxylase OS=Homo sapiens OX=9606 GN=P4HTM PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03227	GILT	Gamma interferon inducible lysosomal thiol reductase (GILT)	Family	Interproscan
PF13640	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004911	Family	Gamma interferon inducible lysosomal thiol reductase GILT	Interproscan
IPR045054	Family	Prolyl 4-hydroxylase	Interproscan
IPR006620	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan
IPR044862	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10869	PROLYL 4-HYDROXYLASE ALPHA SUBUNIT	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0016671	Molecular Function	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	Interproscan
GO:0004656	Molecular Function	procollagen-proline 4-dioxygenase activity	Interproscan
GO:0005783	Cellular Component	endoplasmic reticulum	Interproscan
GO:0018401	Biological Process	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Interproscan
GO:0005506	Molecular Function	iron ion binding	Interproscan
GO:0016705	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418	Molecular Function	L-ascorbic acid binding	Interproscan