Gene detail

Detailed information of ANN21692-RA in Montipora grisea

Genomic Location: Scaffold_17__1_contigs__length_5665553:4121093...4124767
NR annotation: RKU35139.1, methionine synthase [Candidatus Poribacteria bacterium]
Species Montipora grisea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ANN21692-RA

ATGACAGATTCTAAACAAATAACACACCTTAAAAATGAACTAAAGAAGCGGATTCTGGTTCTTGATGGGGCAATGGGGTCTCTGTTGCAAACTTATCGACTGACAGAGGCAGATTTTCGAGGTAAACAGTTTGCTGACCATCCGTGCGAACTTAAAGGTTATAACGACCTGCTCTCCATAACCCAACCGCACATCGTCCAAGAAATACACGCGAACTATTGTAGCGCGGGTGCTGACATTATCGAAACGAATACTTTTACCAGCACATCCGTGTCAATGGCAGATTACCAGCTCCAGGACATTGCGTATCAGATAAACTACGAAGCGGCACGTATCGCTCGCGAAGTAGCAGATAAATGGACCTCACCGGATAAACCACGCTTTGTCGCTGGAAGCATGGGACCTACCAATCGCAGTTGCTCAATTTCGCCAAACGTGAACGATCCCGGCTATCGGAATATCACCTTCTCACAACTCGTTTCTGCTTATACAACACAAGCGGAGGGTTTAATTGATGGAGGTGCTGATCTCCTCCTCGTCGAAACCGTCATGGATACGCTTAATTGTAAAGCGGCACTCTTCGCTATACAGACCCTCGCTGAAATACGAAGCATCGACATCCCGATCATCGTCTCGTCTGATAGGAGCGGTGGCGGCGGCAGAAATCTTTCTGGACAAACAGTTGAAGCCTTTTGGAACTCCGTTCGGCACGCCAACCTGCTTGCCGTTGGGTTGAACTGTGGTTTTGGTTCCCAGCAGATTCGCCCGTACCTTGCCGAGATGGCAAAAATGACTGACCTCCCGGTTATTTGCTATCCCAATGCTGGATTGCCCAACGAACTCGGTCAGTACACACAGTCCCCAGAAGAAATGGGAAATTGGATACACGAATTTGCACAAAACGGGTTTGTTAACATTGTCGGTGGCTGCTGCGGAAGTCAACCTGAACATATCGAAACGATCGCTAAGGTCGCCGCTGAATATCCACCGCGAGAGCCTGCCCAACAAACGCGCGCCTGCCGACTCAGCGGCTTAGAGGCGTTCAACATTACCTCTGATTCTCTCTTTGTTAACGTTGGGGAACGGACAAACGTAACAGGATCCCGACGATTCGCAACGCTCATTAAAAATGAGGACTATGAGACGGCTTTAGAAATTGCCCGTGACCAAGTAGAAAACGGTGCACAACTTATCGACATCAACATGGACGCTGGCATGTTAGATGCCAAAGCAGCAATGGTTAGGTTTCTCAACCTCATCGCCGCGGAGCCCGATATTAGTAGAGTACCTATCATGCTGGATTCCAGCAGATGGGAGGTAATAGAGGCAGGTTTGGAGTGCATTCAAGGAAAAGGCATCGTCAACTCTATTAGTCTGAAAGAGGGTGAAGCGGATTTCTTAGCAAAGGCGCGCCAGATTCACCGATACGGTGCTGCCGTTATTGTGATGGCATTTGATGAAGAAGGACAAGCCGACACTTACGAACGGAAGGTGGAGATTTGTCGTAGGGCGTATCGACTCTTGACGGAAGGAGTTGGATTCCCGCCGGAGGACATTATTTTTGATCCGAATATTTTCGCTGTCGCGACAGGTATTGAAGAACATAATGCATACGCGAAGGCGTTTATTGAGGCGTGCGAAGAAATTAAAGCCACTTGTCCACACACTTTGGTGAGCGGCGGTGTAAGCAATATTTCATTCGCTTTCCGCGGGAATGACCGTGTCAGAGAAGCGATGCACGCAGCGTTTCTCTATCACGCTATCCATGCGGGTATGGACATGGGAATTGTCAACGCTGGGCAGCTTGCTGTCTATGATGACCTACCAAAAACACTCTTGGAAGCCGTAGAGGATGTCTTATTTAATCGCCGAGAAGATGCGACAGATCAACTCGTTAATCTCGCCAACACACTACAAGGGAAAGGGAAAAAGAAGCGTGTGAGTCGGAAATGGCGAAAATTGTCGGTTGAAGAGAGGCTACGTCACGCACTCGTCGACGGGATTCTCGAATACATTGAAGTCGATACAGAGGAAGCGCGGCAAAACTATGAACGTCCCATACAGGTAATCGAGGGGCCATTGATGGAGGGTATGAACCGGGTTGGTGAACTTTTCGGTGCCGGTAAAATGTTTCTGCCACAAGTCGTCAAAAGCGCGCGGGTCATGAAAAGAGCTGTTGCACACCTCACTCCGTATATTGAACAGGAACAAGCGGAAGGGGGTACCCGATCGAGAGGTAAGATCGTAATGGCGACGGTGAAGGGTGACGTACACGATATTGGGAAGAACATCGTCGGTGTCGTGCTTGGGTGTAACAACTACGAGGTCATAGACCTTGGGGTGATGGTACCTGCAGAAGAAATTTTAGAAAGGGCACGGAAAGAGAACGCTGATATTATCGGGTTGAGTGGTCTCATCACGCCATCGTTAGATGAGATGGTACACGTCGCTGAAGAGATGGAGCGCGAAGGCTTCTGCATTCCGCTTCTCATCGGCGGTGCGACCACCTCAAAAGTACATACAGCCGTTCAGATTGAACCTGCTTATAGTGGACTCACGGTTCACGTCAAAGATGCCTCCCGAAGCGTTGGCATCGTTGGCAACTTGATGAGTCCCGAAAGGCAGCTGGTACTCGCCGAGCAGACGCGCGAAGCGTACGAAGAAATTCGAGAACGCCGAGCGAGAAATCGGAAACAGGCGAATCTGCTACCTTTTGTTGTTGCACAAGAGCGGAAAGTCCCATTGGATTGGCGAAATTATCAACCCCCTATACCTGGCCTGATTGGAACTAAGGTCTTTGACGACTATCCGTTAGCGGAACTCGTTGACTATATCGACTGGAACCCATTCTTTACGACCTGGGGACTTCGCGGTAAGTATCCGAATATATTGGAGAATTTGGAAGTTGGTGAGGAAGCGCGTAAACTTCTTAAAGATGCCGAAACACTCCTCCATACCATTGTTGAAGAGAAAAGGTTGCGGGCACGTGCTGTCGTCGGGCTTTTCCCTGCCAACGGGGTCGGTGAAGATACTGAAATTTACGCAGACGCCGCGCGGACGGTGGCGATCGCCACGCTGCACCATCTGCGTCAACAGACAGAACAGCCCTTTACGCGGCCGAACCTCAGCCTCGGGGATTTCATTGCACCGAAAACAACAGGAATTCAGGATTATATCGGGGCATTTGCTGTGACAACAGGTATCGGTGTGTCGGAACTTTGTGCCGAGTTTGAGGAGAAACAAGACGATTACAACAGCATTATGGTGAAAGCGTTAGCAGACCGTTTAGCGGAAGCCTTCGCGGAGCGGATGCATCAGCACGTCCGCACAGCCCTGTGGGGTTACGCCGGTGATGAGGCGTTGGACAATGAAGCCTTGATTGCCGAAAGATATCGCGGGATTCGGCCCGCACCAGGTTATCCAGCATGTCCCGACCATAACCAAAAGCGGGTGTTGTTTGACGTGTTGAAGGCTACAGAGAACACCGGAATCTCTCTTACCGAAAGTCTGGCGATGTTTCCGGCAGCATCCGTGAGTGGATGGTATTATTCGCATCCTGAGGCGCGGTATTTCAGTATCGGCAGGATTGGTGAGGATCAGGTTGTCGATTATGCAGAACGGACGGGAATGGAATTGGAAACGGCAAGACGCTGGCTGAAGCCGCTGCTTACCTGA

Transcript

ANN21692-RA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P37586	Methionine synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=metH PE=3 SV=3
Q9I2Q2	Methionine synthase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=metH PE=3 SV=1
P13009	Methionine synthase OS=Escherichia coli (strain K12) OX=83333 GN=metH PE=1 SV=5

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002664 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00809 all species →	Pterin_bind	Pterin binding enzyme	Domain	Interproscan
PF02310 all species →	B12-binding	B12 binding domain	Domain	Interproscan
PF02574 all species →	S-methyl_trans	Homocysteine S-methyltransferase	Family	Interproscan
PF02965 all species →	Met_synt_B12	Vitamin B12 dependent methionine synthase, activation domain	Domain	Interproscan
PF02607 all species →	B12-binding_2	B12 binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR033706 all species →	Domain	Methionine synthase, B12-binding domain	Interproscan
IPR036594 all species →	Homologous_superfamily	Methionine synthase domain	Interproscan
IPR000489 all species →	Domain	Pterin-binding domain	Interproscan
IPR011822 all species →	Family	Cobalamin-dependent methionine synthase	Interproscan
IPR006158 all species →	Domain	Cobalamin (vitamin B12)-binding domain	Interproscan
IPR036589 all species →	Homologous_superfamily	Homocysteine-binding domain superfamily	Interproscan
IPR003726 all species →	Domain	Homocysteine-binding domain	Interproscan
IPR011005 all species →	Homologous_superfamily	Dihydropteroate synthase-like superfamily	Interproscan
IPR004223 all species →	Domain	Vitamin B12-dependent methionine synthase, activation domain	Interproscan
IPR036724 all species →	Homologous_superfamily	Cobalamin-binding domain superfamily	Interproscan
IPR050554 all species →	Family	Methionine Synthase/Corrinoid	Interproscan
IPR037010 all species →	Homologous_superfamily	Vitamin B12-dependent methionine synthase, activation domain superfamily	Interproscan
IPR003759 all species →	Domain	Cobalamin (vitamin B12)-binding module, cap domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45833 all species →	METHIONINE SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0031419 all species →	Molecular Function	cobalamin binding	Interproscan
GO:0042558 all species →	Biological Process	pteridine-containing compound metabolic process	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0008705 all species →	Molecular Function	methionine synthase activity	Interproscan
GO:0009086 all species →	Biological Process	methionine biosynthetic process	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0044237 all species →	Biological Process	obsolete cellular metabolic process	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0046653 all species →	Biological Process	tetrahydrofolate metabolic process	Interproscan
GO:0050667 all species →	Biological Process	homocysteine metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00548	metH, MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase	EC:2.1.1.13	Cobalamin transport and metabolism	ko04980	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.