Genomic Location: Scaffold_22__1_contigs__length_3165292:218204...219802
NR annotation: RKU34382.1, citramalate synthase [Candidatus Poribacteria bacterium]
Species Montipora grisea · all data for this species · gene families
| CDS |
| ANN22666-RA |
| Transcript |
| ANN22666-RA |
| Protein |
| ANN22666-RA |
| UniProt accession | Description |
|---|---|
| Q74C76 | (R)-citramalate synthase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) OX=243231 GN=cimA PE=1 SV=1 |
| Q9WZ22 | (R)-citramalate synthase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=cimA PE=3 SV=1 |
| O66682 | (R)-citramalate synthase OS=Aquifex aeolicus (strain VF5) OX=224324 GN=cimA PE=3 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0012804 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08502 all species → | LeuA_dimer | LeuA allosteric (dimerisation) domain | Domain | Interproscan |
| PF00682 all species → | HMGL-like | HMGL-like | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002034 all species → | Conserved_site | Alpha-isopropylmalate/homocitrate synthase, conserved site | Interproscan |
| IPR036230 all species → | Homologous_superfamily | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily | Interproscan |
| IPR013709 all species → | Domain | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | Interproscan |
| IPR013785 all species → | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| IPR000891 all species → | Domain | Pyruvate carboxyltransferase | Interproscan |
| IPR005675 all species → | Family | Citramalate synthase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43538 all species → | ALPHA-IPM SYNTHASE/HOMOCITRATE SYNTHASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0019752 all species → | Biological Process | carboxylic acid metabolic process | Interproscan |
| GO:0046912 all species → | Molecular Function | acyltransferase activity, acyl groups converted into alkyl on transfer | Interproscan |
| GO:0003852 all species → | Molecular Function | 2-isopropylmalate synthase activity | Interproscan |
| GO:0009098 all species → | Biological Process | L-leucine biosynthetic process | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01649 | leuA, IMS; 2-isopropylmalate synthase | EC:2.3.3.13 | Valine, leucine and isoleucine biosynthesis | ko00290 | deepkoala |
Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
