Genomic Location: Scaffold_21__1_contigs__length_3404173:2716159...2717646
NR annotation: MYC94360.1, CoA-acylating methylmalonate-semialdehyde dehydrogenase [Caldilineaceae bacterium SB0661_bin_32]
Species Montipora grisea · all data for this species · gene families
| CDS |
| ANN22985-RA |
| Transcript |
| ANN22985-RA |
| Protein |
| ANN22985-RA |
| UniProt accession | Description |
|---|---|
| Q5KYR4 | Malonate-semialdehyde dehydrogenase 2 OS=Geobacillus kaustophilus (strain HTA426) OX=235909 GN=iolA2 PE=3 SV=2 |
| Q9KAH5 | Malonate-semialdehyde dehydrogenase OS=Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=iolA PE=3 SV=1 |
| A4IPB2 | Malonate-semialdehyde dehydrogenase 1 OS=Geobacillus thermodenitrificans (strain NG80-2) OX=420246 GN=iolA1 PE=3 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004065 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00171 all species → | Aldedh | Aldehyde dehydrogenase family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR010061 all species → | Family | Methylmalonate-semialdehyde dehydrogenase | Interproscan |
| IPR016162 all species → | Homologous_superfamily | Aldehyde dehydrogenase, N-terminal | Interproscan |
| IPR016160 all species → | Conserved_site | Aldehyde dehydrogenase, cysteine active site | Interproscan |
| IPR016161 all species → | Homologous_superfamily | Aldehyde/histidinol dehydrogenase | Interproscan |
| IPR016163 all species → | Homologous_superfamily | Aldehyde dehydrogenase, C-terminal | Interproscan |
| IPR015590 all species → | Domain | Aldehyde dehydrogenase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43866 all species → | MALONATE-SEMIALDEHYDE DEHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004491 all species → | Molecular Function | methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0016620 all species → | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0006210 all species → | Biological Process | thymine catabolic process | Interproscan |
| GO:0006574 all species → | Biological Process | valine catabolic process | Interproscan |
| GO:0018478 all species → | Molecular Function | malonate-semialdehyde dehydrogenase (acetylating) activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00140 | mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase | EC:1.2.1.18 EC:1.2.1.27 | beta-Alanine metabolism | ko00410 | deepkoala |
Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
