Genomic Location: Scaffold_31__1_contigs__length_1398629:818636...821237
NR annotation: MCE2393721.1, serine hydroxymethyltransferase [Candidatus Poribacteria bacterium]
| CDS | |||||
| ANN23831-RA | |||||
| Transcript |
| ANN23831-RA |
| Protein |
| ANN23831-RA |
| Uniprot term | Description |
|---|---|
| A0B8J6 | Serine hydroxymethyltransferase OS=Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) OX=349307 GN=glyA PE=3 SV=1 |
| B5YFZ0 | Serine hydroxymethyltransferase OS=Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) OX=289376 GN=glyA PE=3 SV=1 |
| Q3A934 | Serine hydroxymethyltransferase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) OX=246194 GN=glyA PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00464 | SHMT | Serine hydroxymethyltransferase | Domain | Interproscan |
| PF02875 | Mur_ligase_C | Mur ligase family, glutamate ligase domain | Domain | Interproscan |
| PF08245 | Mur_ligase_M | Mur ligase middle domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001645 | Family | Folylpolyglutamate synthetase | Interproscan |
| IPR015424 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase | Interproscan |
| IPR015422 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, small domain | Interproscan |
| IPR019798 | Binding_site | Serine hydroxymethyltransferase, pyridoxal phosphate binding site | Interproscan |
| IPR036565 | Homologous_superfamily | Mur-like, catalytic domain superfamily | Interproscan |
| IPR036615 | Homologous_superfamily | Mur ligase, C-terminal domain superfamily | Interproscan |
| IPR001085 | Family | Serine hydroxymethyltransferase | Interproscan |
| IPR039429 | Domain | Serine hydroxymethyltransferase-like domain | Interproscan |
| IPR018109 | Conserved_site | Folylpolyglutamate synthetase, conserved site | Interproscan |
| IPR004101 | Domain | Mur ligase, C-terminal | Interproscan |
| IPR015421 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, major domain | Interproscan |
| IPR013221 | Domain | Mur ligase, central | Interproscan |
| IPR049943 | Family | Serine hydroxymethyltransferase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11680 | SERINE HYDROXYMETHYLTRANSFERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004326 | Molecular Function | tetrahydrofolylpolyglutamate synthase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0009396 | Biological Process | folic acid-containing compound biosynthetic process | Interproscan |
| GO:0030170 | Molecular Function | pyridoxal phosphate binding | Interproscan |
| GO:0009058 | Biological Process | biosynthetic process | Interproscan |
| GO:0016881 | Molecular Function | acid-amino acid ligase activity | Interproscan |
| GO:0004372 | Molecular Function | glycine hydroxymethyltransferase activity | Interproscan |
| GO:0019264 | Biological Process | glycine biosynthetic process from serine | Interproscan |
| GO:0035999 | Biological Process | tetrahydrofolate interconversion | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006565 | Biological Process | L-serine catabolic process | Interproscan |
| GO:0006730 | Biological Process | one-carbon metabolic process | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0046653 | Biological Process | tetrahydrofolate metabolic process | Interproscan |
| GO:0046655 | Biological Process | folic acid metabolic process | Interproscan |
| GO:0050897 | Molecular Function | cobalt ion binding | Interproscan |
| GO:0070905 | Molecular Function | serine binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11754 | folC; dihydrofolate synthase / folylpolyglutamate synthase | EC:6.3.2.12 EC:6.3.2.17 | Folate biosynthesis | ko00790 | deepkoala |