Gene detail

Detailed information of ANN25638-RA in Montipora grisea

Genomic Location: Scaffold_906__1_contigs__length_68442:29385...30275
NR annotation: WP_166167041.1, 3-hydroxyisobutyrate dehydrogenase [Pseudomaricurvus alcaniphilus]
Species Montipora grisea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P28811	3-hydroxyisobutyrate dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=mmsB PE=1 SV=1
Q9I5I6	NAD-dependent L-serine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=PA0743 PE=1 SV=1
Q54CX6	Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Dictyostelium discoideum OX=44689 GN=hibA PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004016 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03446 all species →	NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	Domain	Interproscan
PF14833 all species →	NAD_binding_11	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013328 all species →	Homologous_superfamily	6-phosphogluconate dehydrogenase, domain 2	Interproscan
IPR008927 all species →	Homologous_superfamily	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	Interproscan
IPR002204 all species →	Conserved_site	3-hydroxyisobutyrate dehydrogenase-related, conserved site	Interproscan
IPR006115 all species →	Domain	6-phosphogluconate dehydrogenase, NADP-binding	Interproscan
IPR011548 all species →	Family	3-hydroxyisobutyrate dehydrogenase	Interproscan
IPR015815 all species →	Family	3-hydroxyisobutyrate dehydrogenase-related	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR029154 all species →	Domain	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22981 all species →	3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0016616 all species →	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0008442 all species →	Molecular Function	3-hydroxyisobutyrate dehydrogenase activity	Interproscan
GO:0051287 all species →	Molecular Function	NAD binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00020	HIBADH, mmsB; 3-hydroxyisobutyrate dehydrogenase	EC:1.1.1.31	Valine, leucine and isoleucine degradation	ko00280	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.