Genomic Location: Scaffold_2449__1_contigs__length_42648:34735...36903
NR annotation: MBL4804528.1, NADP-dependent isocitrate dehydrogenase [Alphaproteobacteria bacterium]
| CDS | |||||
| ANN28639-RA | |||||
| Transcript |
| ANN28639-RA |
| Protein |
| ANN28639-RA |
| Uniprot term | Description |
|---|---|
| Q1RJU4 | Isocitrate dehydrogenase [NADP] OS=Rickettsia bellii (strain RML369-C) OX=336407 GN=icd PE=3 SV=1 |
| Q4UKR1 | Isocitrate dehydrogenase [NADP] OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=icd PE=3 SV=2 |
| Q68XA5 | Isocitrate dehydrogenase [NADP] OS=Rickettsia typhi (strain ATCC VR-144 / Wilmington) OX=257363 GN=icd PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF18324 | Isocitrate_DH_C_bact | Bacterial isocitrate dehydrogenase, C-terminal domain | Domain | Interproscan |
| PF00180 | Iso_dh | Isocitrate/isopropylmalate dehydrogenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR040978 | Domain | Isocitrate dehydrogenase/Hypothetical protein TT1725, C-terminal domain | Interproscan |
| IPR024084 | Domain | Isopropylmalate dehydrogenase-like domain | Interproscan |
| IPR014273 | Family | Isocitrate dehydrogenase, bacteria-type | Interproscan |
| IPR046997 | Homologous_superfamily | Isocitrate dehydrogenase/Hypothetical protein TT1725, C-terminal domain superfamily | Interproscan |
| IPR019818 | Conserved_site | Isocitrate/isopropylmalate dehydrogenase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11835 | DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004449 | Molecular Function | isocitrate dehydrogenase (NAD+) activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006099 | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0006102 | Biological Process | isocitrate metabolic process | Interproscan |
| GO:0004450 | Molecular Function | isocitrate dehydrogenase (NADP+) activity | Interproscan |
| GO:0006097 | Biological Process | glyoxylate cycle | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00031 | IDH1, IDH2, icd; isocitrate dehydrogenase | EC:1.1.1.42 | Central carbon metabolism in cancer | ko05230 | deepkoala |