Genomic Location: Scaffold_5514__1_contigs__length_29218:5651...8299
NR annotation: MBL4805453.1, dihydrofolate reductase [Alphaproteobacteria bacterium]
| CDS | |||||
| ANN32083-RA | |||||
| Transcript |
| ANN32083-RA |
| Protein |
| ANN32083-RA |
| Uniprot term | Description |
|---|---|
| Q6REU8 | Thymidylate synthase OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6) OX=406817 GN=thyA PE=3 SV=1 |
| B7GI39 | Thymidylate synthase OS=Anoxybacillus flavithermus (strain DSM 21510 / WK1) OX=491915 GN=thyA PE=3 SV=1 |
| A4INY1 | Thymidylate synthase OS=Geobacillus thermodenitrificans (strain NG80-2) OX=420246 GN=thyA PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| PF00303 | Thymidylat_synt | Thymidylate synthase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001796 | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR024072 | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| IPR045097 | Family | Thymidylate synthase/dCMP hydroxymethylase | Interproscan |
| IPR000398 | Family | Thymidylate synthase | Interproscan |
| IPR036926 | Homologous_superfamily | Thymidylate synthase/dCMP hydroxymethylase superfamily | Interproscan |
| IPR023451 | Domain | Thymidylate synthase/dCMP hydroxymethylase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11548 | THYMIDYLATE SYNTHASE 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004146 | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0004799 | Molecular Function | thymidylate synthase activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006231 | Biological Process | dTMP biosynthetic process | Interproscan |
| GO:0016741 | Molecular Function | transferase activity, transferring one-carbon groups | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00287 | DHFR, folA; dihydrofolate reductase | EC:1.5.1.3 | Antifolate resistance | ko01523 | deepkoala |