Genomic Location: Scaffold_5843__1_contigs__length_28425:22865...24268
NR annotation: MCE2485945.1, 3-isopropylmalate dehydratase large subunit [Desulfurellaceae bacterium]
Species Montipora grisea · all data for this species · gene families
| CDS |
| ANN34697-RA |
| Transcript |
| ANN34697-RA |
| Protein |
| ANN34697-RA |
| UniProt accession | Description |
|---|---|
| A0L8J4 | 3-isopropylmalate dehydratase large subunit OS=Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) OX=156889 GN=leuC PE=3 SV=1 |
| Q3SHL1 | 3-isopropylmalate dehydratase large subunit OS=Thiobacillus denitrificans (strain ATCC 25259 / T1) OX=292415 GN=leuC PE=3 SV=1 |
| B8GQD6 | 3-isopropylmalate dehydratase large subunit OS=Thioalkalivibrio sulfidiphilus (strain HL-EbGR7) OX=396588 GN=leuC PE=3 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0013548 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00330 all species → | Aconitase | Aconitase family (aconitate hydratase) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015931 all species → | Homologous_superfamily | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 | Interproscan |
| IPR033941 all species → | Domain | 3-Isopropylmalate dehydratase, catalytic domain | Interproscan |
| IPR004430 all species → | Family | 3-isopropylmalate dehydratase, large subunit | Interproscan |
| IPR050067 all species → | Family | Isopropylmalate dehydratase and related enzymes | Interproscan |
| IPR001030 all species → | Domain | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain | Interproscan |
| IPR018136 all species → | Binding_site | Aconitase family, 4Fe-4S cluster binding site | Interproscan |
| IPR036008 all species → | Homologous_superfamily | Aconitase, iron-sulfur domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43822 all species → | HOMOACONITASE, MITOCHONDRIAL-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003861 all species → | Molecular Function | 3-isopropylmalate dehydratase activity | Interproscan |
| GO:0009098 all species → | Biological Process | L-leucine biosynthetic process | Interproscan |
| GO:0051539 all species → | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01703 | leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | EC:4.2.1.33 EC:4.2.1.35 | Glucosinolate biosynthesis | ko00966 | deepkoala |
Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
