Gene detail

Detailed information of ANN37565-RA in Montipora grisea

Genomic Location: Scaffold_5505__1_contigs__length_29237:23996...26884
NR annotation: MAZ86905.1, 2-isopropylmalate synthase [Cellvibrionaceae bacterium]
Species Montipora grisea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ANN37565-RA

ATGTTGGCGGTGTGCTTTATCGATTTAGACGGCTTTAAGCCCGTCAATGATCGTTACGGTCACCCGGCGGGAGATCAATTGTTGGTGGAGATTGCGCGCCGCTTGGAAGATGTGGTGCGCAGTGAAGACACGGTTGCGCGCCTTGGGGGTGATGAGTTTGTGTTGTTACTCACGCGCTTGTCTGATATCGATGAGTTGGATGCTGCTCTAGAGAGGGTGCATGGCGCAATTACTCGCACGGTGGTGGTGGAAAGGCAGCCGCTGAAGGTCACCGCCAGTATTGGTGTGTCGCTGTACCCTCAGGATGATGTTGATGCCGATACTCTTATACGGCACGCCGACATGGCAATGTATGAGGCGAAGCAGTCGGGTCGCAATCGCTATCACCTGTTTGACGCCTCTCTGGATCGTCAGATCCATGCGCGCCATCGCCAAATTGAACGGATGACACAGGCTCTGGCGGAAAATGAATTTGTGTTGTTTTATCAGCCGAAGGTGAACCTGGTCAGCGGCCGTGTGCTTGGGGTTGAGGCGCTGATTCGATGGCAACACCCGAGACGGGGGTTGTTAGAGCCGATGAGTTTCCTGCCGCTGATTGAATCCCATGATCTGATGTTGTCATTAGGGGATTGGGTGGTGAATGAGGCGATGGCGCAGGTCGCGGCGTGGAAACTGTCAGGTTTCGACCTCCAAGTGGGCATCAATCTCGCTGCGCGGCAAATCGAAGACCCCGCGTTCATTGATCGACTGGAGGCGGCTTTCGAGCGCCACCCTTCAGTGAATGGCGACATGATTGAGTTTGAGATATTGGAAACCTCGGCCGTCGATGCTGATCAAATATCGTCGTTGGTGAATGAAGCGTCCGCGAGATTTGATGTGTCTTTCGCCTTGGATGATTTCGGTACGGGTTATTCCTCGTTGGCCTATTTGAAAAAGCTGCCGGCAACGGCACTGAAAATTGATCAGACCTTTGTGCGAGATATGCTTGAAGACATGGAAGATCAGGCGATTGTGAAAGGTGTGATTGAGTTGGCTCGAGTGTTTGGTCGTACGGTTGTCGCCGAGGGCGTTGAGACCGATGCGCACGCCAGCAAACTGCTGGAGTTTGGTTGTGAGGTGGCGCAAGGCTACGGTATCTCGAAGCCGATGCCCGCTGATAAAGTGTGCGCCTGGGTGGCCAACTACAGTGGCGGCCTAAAGCGGGTGGATAAAACACACATTACAGTTGCCGTGCGTGTGTGCACGGAGAGGATAGTGATTGTGAACAAAGACAAATTGATTATTTTTGATACAACCTTGCGCGACGGTGAGCAAAGCCCGGGCGCATCCATGACTTTGGAAGAAAAAGTCCGCATTGCGAAAATGTTGGAAAAAATGCGGGTTGATGTGATTGAGGCTGGCTTCGCCATTGCCAGTAAAGGGGATTTTGAGGCAGTTCAGGCTGTTGCCGCTGCGGTGAAAAATTCTCGCGTGTGCAGCTTGGCGAGAGCGGGAAGGATGGATATTGAGCGAGCAGGAGAGGCGTTGAAAAAGGCCAATGCCGGTCGTATTCATACGTTTATCGCTACTTCTCCGATCCACATGAAATACAAATTGCAGATGTTGCCAGAGCAGGTGTTGGAGCAGGCTGTAGAGGCGGTAAAAATTGCCCGCAATTTGTGCGATGACGTGGAGTTCTCTCTGGAGGATGGCAGCCGCACTGAGCCGGAGTTTATGTACCGTATCATCGAAGCGGTCATTAACGCCGGTGCGGGTACGGTGAATATTCCAGACACTGTGGGTTACGGTGTGCCAGAGGAATACGGCGCGATGTTCCGCAACGTGATTGAAAATGTACCCAATTCAGACAAAGCCATCTTTTCTGCCCATTGTCACAATGATTTGGGGTTGGCCGTGGCGAATTCCTTGGCGTCTGTGATGAATGGCGTGCGACAGGTAGAGTGCACTATCAATGGTCTGGGGGAGCGTGCGGGCAATGCCGCGTTGGAAGAGATCGTGATGGCCACTCGCACAAGAACCGATTTTTACCCGGTCGATACCGCCATTGATGCGACTCAGATTGTTCCCACATCGCGGTTGGTGGCCAGCATCACAGGCTTCCCTGTGCAGCCTAATAAGGCTGTGGTAGGGGCTAACGCTTTCGCTCATGAGAGCGGCATTCATCAGGATGGCGTGCTGAAGCACCGAGAAACGTACGAAATTATGCGTGCTCAGGATGTTGGCTGGAACACCAACAAATTGGTGTTGGGTAAGCACTCCGGACGAGCGGCGGTGCGGGCGCGATTTGAAGAATTAGGCATCACTTTTGAGACGCCCGAGCAGCTTCACGAGGTGTTTGCTCGATTCAAAGAATTGGCTGACAAAAAGCACGAGATTTTCGATGAAGATTTGCAGTCCTTGGTGGTAGGTGCTGGCGAGCGCTCAGAGAGTGAGGTTTACGCGTTCAAATCTATGGAGGTGTCGTGTAAAACCGGCAGTAAACCTCACGCCGCTTTAACTTTTACCCCGCCACGGCGAAGTAATTACGACGTCTGCGGATGGCAGTGGCCCGGTAGACGCTGTGTTTAA

Transcript

ANN37565-RA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2YBW0	2-isopropylmalate synthase OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) OX=323848 GN=leuA PE=3 SV=1
Q605K7	2-isopropylmalate synthase OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) OX=243233 GN=leuA PE=3 SV=1
Q3J877	2-isopropylmalate synthase OS=Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107) OX=323261 GN=leuA PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0012989 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00990 all species →	GGDEF	Diguanylate cyclase, GGDEF domain	Domain	Interproscan
PF00563 all species →	EAL	EAL domain	Domain	Interproscan
PF00682 all species →	HMGL-like	HMGL-like	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002034 all species →	Conserved_site	Alpha-isopropylmalate/homocitrate synthase, conserved site	Interproscan
IPR000160 all species →	Domain	GGDEF domain	Interproscan
IPR043128 all species →	Homologous_superfamily	Reverse transcriptase/Diguanylate cyclase domain	Interproscan
IPR001633 all species →	Domain	EAL domain	Interproscan
IPR035919 all species →	Homologous_superfamily	EAL domain superfamily	Interproscan
IPR029787 all species →	Homologous_superfamily	Nucleotide cyclase	Interproscan
IPR000891 all species →	Domain	Pyruvate carboxyltransferase	Interproscan
IPR050073 all species →	Family	Alpha-IPM synthase/homocitrate synthase	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan
IPR005671 all species →	Family	2-isopropylmalate synthase, bacterial-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10277 all species →	HOMOCITRATE SYNTHASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019752 all species →	Biological Process	carboxylic acid metabolic process	Interproscan
GO:0046912 all species →	Molecular Function	acyltransferase activity, acyl groups converted into alkyl on transfer	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0003852 all species →	Molecular Function	2-isopropylmalate synthase activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0009098 all species →	Biological Process	L-leucine biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01649	leuA, IMS; 2-isopropylmalate synthase	EC:2.3.3.13	Valine, leucine and isoleucine biosynthesis	ko00290	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.