Detailed information of ANN39138-RA in Montipora grisea

Genomic Location: Scaffold_2908__1_contigs__length_39261:762...1516
NR annotation: OHD22923.1, GTP cyclohydrolase I FolE [Spirochaetes bacterium GWB1_59_5]
Species Montipora grisea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q2Y6B3GTP cyclohydrolase 1 OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) OX=323848 GN=folE PE=3 SV=1
A6SZ52GTP cyclohydrolase 1 OS=Janthinobacterium sp. (strain Marseille) OX=375286 GN=folE PE=3 SV=1
Q7M933GTP cyclohydrolase 1 OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 / NCTC 11488 / FDC 602W) OX=273121 GN=folE PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003626 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01227
all species →
GTP_cyclohydroIGTP cyclohydrolase IDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR043133
all species →
Homologous_superfamilyGTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductaseInterproscan
IPR018234
all species →
Conserved_siteGTP cyclohydrolase I, conserved siteInterproscan
IPR020602
all species →
DomainGTP cyclohydrolase I domainInterproscan
IPR001474
all species →
FamilyGTP cyclohydrolase IInterproscan
IPR043134
all species →
Homologous_superfamilyGTP cyclohydrolase I, N-terminal domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11109
all species →
GTP CYCLOHYDROLASE IInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003934
all species →
Molecular FunctionGTP cyclohydrolase I activityInterproscan
GO:0046654
all species →
Biological Processtetrahydrofolate biosynthetic processInterproscan
GO:0005525
all species →
Molecular FunctionGTP bindingInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0006729
all species →
Biological Processtetrahydrobiopterin biosynthetic processInterproscan
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01495GCH1, folE; GTP cyclohydrolase IAEC:3.5.4.16
Folate biosynthesisko00790deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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