Detailed information of ANN40940-RA in Montipora grisea

Genomic Location: Scaffold_9161__1_contigs__length_20375:19311...20228
NR annotation: MYH71472.1, hydroxymethylglutaryl-CoA lyase [Acidimicrobiia bacterium]
Species Montipora grisea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P13703Hydroxymethylglutaryl-CoA lyase OS=Pseudomonas mevalonii OX=32044 GN=mvaB PE=3 SV=1
A9WGE2(R)-citramalyl-CoA lyase OS=Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) OX=324602 GN=ccl PE=1 SV=1
O34873Hydroxymethylglutaryl-CoA lyase YngG OS=Bacillus subtilis (strain 168) OX=224308 GN=yngG PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003375 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00682
all species →		HMGL-likeHMGL-likeDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000891
all species →		DomainPyruvate carboxyltransferaseInterproscan
IPR043594
all species →		FamilyHMG-CoA lyaseInterproscan
IPR013785
all species →		Homologous_superfamilyAldolase-type TIM barrelInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR42738
all species →		HYDROXYMETHYLGLUTARYL-COA LYASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003824
all species →		Molecular Functioncatalytic activityInterproscan
GO:0004419
all species →		Molecular Functionhydroxymethylglutaryl-CoA lyase activityInterproscan
GO:0006552
all species →		Biological ProcessL-leucine catabolic processInterproscan
GO:0016833
all species →		Molecular Functionoxo-acid-lyase activityInterproscan
GO:0046951
all species →		Biological Processketone body biosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01640HMGCL, hmgL; hydroxymethylglutaryl-CoA lyaseEC:4.1.3.4
Peroxisomeko04146deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora grisea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora grisea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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