Genomic Location: :...
NR annotation: MCP4268470.1, GIY-YIG nuclease family protein [Candidatus Brocadiaceae bacterium]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q9HD20 | Endoplasmic reticulum transmembrane helix translocase OS=Homo sapiens OX=9606 GN=ATP13A1 PE=1 SV=2 | ||||
| Q9EPE9 | Endoplasmic reticulum transmembrane helix translocase OS=Mus musculus OX=10090 GN=Atp13a1 PE=1 SV=2 | ||||
| P90747 | Probable manganese-transporting ATPase catp-8 OS=Caenorhabditis elegans OX=6239 GN=catp-8 PE=3 SV=3 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | bHLH |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00293 | NUDIX | NUDIX domain | Domain | Interproscan |
| PF12838 | Fer4_7 | 4Fe-4S dicluster domain | Domain | Interproscan |
| PF03564 | DUF1759 | Protein of unknown function (DUF1759) | Family | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF00010 | HLH | Helix-loop-helix DNA-binding domain | Domain | Interproscan |
| PF17921 | Integrase_H2C2 | Integrase zinc binding domain | Domain | Interproscan |
| PF00665 | rve | Integrase core domain | Domain | Interproscan |
| PF05729 | NACHT | NACHT domain | Domain | Interproscan |
| PF17919 | RT_RNaseH_2 | RNase H-like domain found in reverse transcriptase | Domain | Interproscan |
| PF10431 | ClpB_D2-small | C-terminal, D2-small domain, of ClpB protein | Domain | Interproscan |
| PF00122 | E1-E2_ATPase | E1-E2 ATPase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015797 | Homologous_superfamily | NUDIX hydrolase-like domain superfamily | Interproscan |
| IPR000086 | Domain | NUDIX hydrolase domain | Interproscan |
| IPR017900 | Conserved_site | 4Fe-4S ferredoxin, iron-sulphur binding, conserved site | Interproscan |
| IPR017896 | Domain | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | Interproscan |
| IPR010226 | Family | NADH-quinone oxidoreductase, chain I | Interproscan |
| IPR005312 | Family | Protein of unknown function DUF1759 | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR036638 | Homologous_superfamily | Helix-loop-helix DNA-binding domain superfamily | Interproscan |
| IPR011598 | Domain | Myc-type, basic helix-loop-helix (bHLH) domain | Interproscan |
| IPR050283 | Family | E-box Binding Transcriptional Regulators | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR041588 | Domain | Integrase zinc-binding domain | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| IPR007111 | Domain | NACHT nucleoside triphosphatase | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR052752 | Family | NACHT and WD repeat domain-containing protein | Interproscan |
| IPR052510 | Family | Oomycete RxLR Effector | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR041577 | Domain | Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain | Interproscan |
| IPR052958 | Family | Interferon-induced PKR regulator | Interproscan |
| IPR050052 | Family | ATP-dependent Clp protease ATP-binding subunit ClpX | Interproscan |
| IPR019489 | Domain | Clp ATPase, C-terminal | Interproscan |
| IPR008250 | Homologous_superfamily | P-type ATPase, A domain superfamily | Interproscan |
| IPR006544 | Family | P-type ATPase, subfamily V | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10849 | NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR23349 | BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST | Interproscan |
| PTHR35450 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR38681 | RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED | Interproscan |
| PTHR19871 | BETA TRANSDUCIN-RELATED PROTEIN | Interproscan |
| PTHR45895 | INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR46289 | 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED | Interproscan |
| PTHR48102 | ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED | Interproscan |
| PTHR45630 | CATION-TRANSPORTING ATPASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0016651 | Molecular Function | oxidoreductase activity, acting on NAD(P)H | Interproscan |
| GO:0051539 | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0003954 | Molecular Function | NADH dehydrogenase activity | Interproscan |
| GO:0005747 | Cellular Component | obsolete mitochondrial respiratory chain complex I | Interproscan |
| GO:0006120 | Biological Process | mitochondrial electron transport, NADH to ubiquinone | Interproscan |
| GO:0009060 | Biological Process | aerobic respiration | Interproscan |
| GO:0032981 | Biological Process | mitochondrial respiratory chain complex I assembly | Interproscan |
| GO:0045272 | Cellular Component | obsolete plasma membrane respiratory chain complex I | Interproscan |
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0000977 | Molecular Function | RNA polymerase II transcription regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0032502 | Biological Process | developmental process | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005759 | Cellular Component | mitochondrial matrix | Interproscan |
| GO:0051603 | Biological Process | proteolysis involved in protein catabolic process | Interproscan |
| GO:0006874 | Biological Process | intracellular calcium ion homeostasis | Interproscan |
| GO:0015662 | Molecular Function | P-type ion transporter activity | Interproscan |
| GO:0019829 | Molecular Function | ATPase-coupled monoatomic cation transmembrane transporter activity | Interproscan |
| GO:0030176 | Cellular Component | obsolete integral component of endoplasmic reticulum membrane | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:0140358 | Molecular Function | P-type transmembrane transporter activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K03941 | NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 | EC:7.1.1.2 | Enzymes with EC numbers | - | deepkoala |
| Non-alcoholic fatty liver disease | ko04932 | deepkoala |