Genomic Location: :...
NR annotation: XP_047124880.1, epidermal growth factor receptor kinase substrate 8-like isoform X5 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q8TE67 | Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Homo sapiens OX=9606 GN=EPS8L3 PE=1 SV=2 | ||||
| Q91WL0 | Epidermal growth factor receptor kinase substrate 8-like protein 3 OS=Mus musculus OX=10090 GN=Eps8l3 PE=2 SV=1 | ||||
| Q8TE68 | Epidermal growth factor receptor kinase substrate 8-like protein 1 OS=Homo sapiens OX=9606 GN=EPS8L1 PE=1 SV=3 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00169 | PH | PH domain | Domain | Interproscan |
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF01163 | RIO1 | RIO1 family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR039801 | Family | Epidermal growth factor receptor kinase substrate 8-like | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR039039 | Family | RAI1-like family | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR036034 | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR001478 | Domain | PDZ domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR043366 | Family | HECTD4 | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR017407 | Family | Serine/threonine-protein kinase Rio1 | Interproscan |
| IPR051272 | Family | RIO-type Ser/Thr kinase | Interproscan |
| IPR000687 | Domain | RIO kinase | Interproscan |
| IPR018935 | Conserved_site | RIO kinase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12287 | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN | Interproscan |
| PTHR12395 | DOM-3 RELATED | Interproscan |
| PTHR36867 | MCG131172, ISOFORM CRA_A | Interproscan |
| PTHR46435 | E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED | Interproscan |
| PTHR45723 | SERINE/THREONINE-PROTEIN KINASE RIO1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003779 | Molecular Function | actin binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007266 | Biological Process | Rho protein signal transduction | Interproscan |
| GO:0035023 | Biological Process | regulation of Rho protein signal transduction | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000956 | Biological Process | nuclear-transcribed mRNA catabolic process | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0034353 | Molecular Function | mRNA 5'-diphosphatase activity | Interproscan |
| GO:0090305 | Biological Process | obsolete nucleic acid phosphodiester bond hydrolysis | Interproscan |
| GO:0110155 | Biological Process | NAD-cap decapping | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0030490 | Biological Process | maturation of SSU-rRNA | Interproscan |
| GO:0030688 | Cellular Component | preribosome, small subunit precursor | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07178 | RIOK1; RIO kinase 1 | EC:2.7.11.1 | Ribosome biogenesis | ko03009 | deepkoala |