Genomic Location: :...
NR annotation: KAJ8028968.1, putative E3 ubiquitin-protein ligase HERC1 [Holothuria leucospilota]
| CDS | ||||
| Transcript |
| Protein |
| Uniprot term | Description | |||
|---|---|---|---|---|
| Q15751 | Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens OX=9606 GN=HERC1 PE=1 SV=2 | |||
| Q4U2R1 | E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3 | |||
| O95714 | E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF00086 | Thyroglobulin_1 | Thyroglobulin type-1 repeat | Domain | Interproscan |
| PF03189 | Otopetrin | Otopetrin | Family | Interproscan |
| PF17921 | Integrase_H2C2 | Integrase zinc binding domain | Domain | Interproscan |
| PF05585 | DUF1758 | Putative peptidase (DUF1758) | Family | Interproscan |
| PF14529 | Exo_endo_phos_2 | Endonuclease-reverse transcriptase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR042469 | Family | E3 ubiquitin-protein ligase HECTD3 | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR026630 | Family | EPM2A-interacting protein 1/ZBED8-like | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR036857 | Homologous_superfamily | Thyroglobulin type-1 superfamily | Interproscan |
| IPR000716 | Domain | Thyroglobulin type-1 | Interproscan |
| IPR051950 | Family | Developmental regulator and protease inhibitor | Interproscan |
| IPR004878 | Family | Otopetrin | Interproscan |
| IPR041588 | Domain | Integrase zinc-binding domain | Interproscan |
| IPR008737 | Domain | Peptidase aspartic, putative | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR005135 | Domain | Endonuclease/exonuclease/phosphatase | Interproscan |
| IPR027124 | Family | SWR1-complex protein 5/Craniofacial development protein 1/2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46654 | E3 UBIQUITIN-PROTEIN LIGASE HECTD3 | Interproscan |
| PTHR33332 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR45913 | EPM2A-INTERACTING PROTEIN 1 | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR12352 | SECRETED MODULAR CALCIUM-BINDING PROTEIN | Interproscan |
| PTHR21522 | PROTON CHANNEL OTOP | Interproscan |
| PTHR22955 | RETROTRANSPOSON | Interproscan |
| PTHR23227 | BUCENTAUR RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0015252 | Molecular Function | proton channel activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0016021 | Cellular Component | membrane | Interproscan |
| GO:1902600 | Biological Process | proton transmembrane transport | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006338 | Biological Process | chromatin remodeling | Interproscan |