Genomic Location: :...
NR annotation: XP_053167420.1, 52 kDa repressor of the inhibitor of the protein kinase-like [Hemicordylus capensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q13905 | Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3 | ||||
| O77086 | Guanine nucleotide-releasing factor 2 OS=Drosophila melanogaster OX=7227 GN=C3G PE=1 SV=4 | ||||
| Q8IS15 | Ras guanine nucleotide exchange factor I OS=Dictyostelium discoideum OX=44689 GN=gefI PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Alpha-Helix|CUE |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF17919 | RT_RNaseH_2 | RNase H-like domain found in reverse transcriptase | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF02845 | CUE | CUE domain | Domain | Interproscan |
| PF00076 | RRM_1 | RNA recognition motif | Domain | Interproscan |
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR021109 | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR001878 | Domain | Zinc finger, CCHC-type | Interproscan |
| IPR036875 | Homologous_superfamily | Zinc finger, CCHC-type superfamily | Interproscan |
| IPR041577 | Domain | Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR040192 | Family | CUE domain-containing protein 1 | Interproscan |
| IPR003892 | Domain | Ubiquitin system component CUE | Interproscan |
| IPR009060 | Homologous_superfamily | UBA-like superfamily | Interproscan |
| IPR000504 | Domain | RNA recognition motif domain | Interproscan |
| IPR035979 | Homologous_superfamily | RNA-binding domain superfamily | Interproscan |
| IPR012677 | Homologous_superfamily | Nucleotide-binding alpha-beta plait domain superfamily | Interproscan |
| IPR002052 | Conserved_site | DNA methylase, N-6 adenine-specific, conserved site | Interproscan |
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR019804 | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR21301 | REVERSE TRANSCRIPTASE | Interproscan |
| PTHR13467 | CUE DOMAIN CONTAINING PROTEIN 1 | Interproscan |
| PTHR48032 | RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 | Interproscan |
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0003729 | Molecular Function | mRNA binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005844 | Cellular Component | obsolete polysome | Interproscan |
| GO:0006417 | Biological Process | regulation of translation | Interproscan |
| GO:0008168 | Molecular Function | methyltransferase activity | Interproscan |
| GO:0032259 | Biological Process | methylation | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11663 | ZNHIT1, VPS71; zinc finger HIT domain-containing protein 1 | - | Renal cell carcinoma | ko05211 | deepkoala |
| Messenger RNA biogenesis | ko03019 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala |