Genomic Location: :...
NR annotation: XP_010205640.1, PREDICTED: DNA polymerase epsilon catalytic subunit A-like, partial [Colius striatus]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q07864 | DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5 |
| Q9WVF7 | DNA polymerase epsilon catalytic subunit A OS=Mus musculus OX=10090 GN=Pole PE=1 SV=3 |
| Q9VCN1 | DNA polymerase epsilon catalytic subunit 1 OS=Drosophila melanogaster OX=7227 GN=PolE1 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14529 | Exo_endo_phos_2 | Endonuclease-reverse transcriptase | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF04752 | ChaC | ChaC-like protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005135 | Domain | Endonuclease/exonuclease/phosphatase | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR029703 | Family | DNA polymerase epsilon catalytic subunit | Interproscan |
| IPR042087 | Homologous_superfamily | DNA polymerase family B, thumb domain | Interproscan |
| IPR002153 | Family | Transient receptor potential channel, canonical | Interproscan |
| IPR036568 | Homologous_superfamily | Gamma-glutamyl cyclotransferase-like superfamily | Interproscan |
| IPR006840 | Family | Glutathione-specific gamma-glutamylcyclotransferase | Interproscan |
| IPR013024 | Domain | Gamma-glutamyl cyclotransferase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46670 | ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR10670 | DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | Interproscan |
| PTHR19446 | REVERSE TRANSCRIPTASES | Interproscan |
| PTHR10117 | TRANSIENT RECEPTOR POTENTIAL CHANNEL | Interproscan |
| PTHR12192 | CATION TRANSPORT PROTEIN CHAC-RELATED | Interproscan |
| PTHR35450 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0000278 | Biological Process | mitotic cell cycle | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0003887 | Molecular Function | DNA-directed DNA polymerase activity | Interproscan |
| GO:0006260 | Biological Process | DNA replication | Interproscan |
| GO:0006272 | Biological Process | leading strand elongation | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006287 | Biological Process | base-excision repair, gap-filling | Interproscan |
| GO:0006297 | Biological Process | nucleotide-excision repair, DNA gap filling | Interproscan |
| GO:0008310 | Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | Interproscan |
| GO:0008622 | Cellular Component | epsilon DNA polymerase complex | Interproscan |
| GO:0045004 | Biological Process | DNA replication proofreading | Interproscan |
| GO:0005262 | Molecular Function | calcium channel activity | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0015279 | Molecular Function | store-operated calcium channel activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0034703 | Cellular Component | cation channel complex | Interproscan |
| GO:0051480 | Biological Process | regulation of cytosolic calcium ion concentration | Interproscan |
| GO:0070588 | Biological Process | calcium ion transmembrane transport | Interproscan |
| GO:0070679 | Molecular Function | inositol 1,4,5 trisphosphate binding | Interproscan |
| GO:0006751 | Biological Process | glutathione catabolic process | Interproscan |
| GO:0061928 | Molecular Function | glutathione specific gamma-glutamylcyclotransferase activity | Interproscan |
| GO:0003839 | Molecular Function | gamma-glutamylcyclotransferase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07232 | CHAC, chaC; glutathione-specific gamma-glutamylcyclotransferase | EC:4.3.2.7 | Glutathione metabolism | ko00480 | deepkoala |