Genomic Location: :...
NR annotation: KAJ8363603.1, hypothetical protein SKAU_G00124340 [Synaphobranchus kaupii]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q9W1K5 | Sestrin homolog OS=Drosophila melanogaster OX=7227 GN=Sesn PE=1 SV=2 | ||||
| Q4R6P7 | Sestrin-1 OS=Macaca fascicularis OX=9541 GN=SESN1 PE=2 SV=1 | ||||
| Q9Y6P5 | Sestrin-1 OS=Homo sapiens OX=9606 GN=SESN1 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | Miscellaneous |
| Transcription Factors Family | RXR-like |
| Transcription Factors Family | THR-like |
| Transcription Factors Family | GCNF-like |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF04636 | PA26 | PA26 p53-induced protein (sestrin) | Family | Interproscan |
| PF00105 | zf-C4 | Zinc finger, C4 type (two domains) | Domain | Interproscan |
| PF00104 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor | Domain | Interproscan |
| PF00106 | adh_short | short chain dehydrogenase | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF09735 | Nckap1 | Nck-associated protein 1 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006730 | Family | Sestrin | Interproscan |
| IPR026630 | Family | EPM2A-interacting protein 1/ZBED8-like | Interproscan |
| IPR001628 | Domain | Zinc finger, nuclear hormone receptor-type | Interproscan |
| IPR035500 | Homologous_superfamily | Nuclear hormone receptor-like domain superfamily | Interproscan |
| IPR000536 | Domain | Nuclear hormone receptor, ligand-binding domain | Interproscan |
| IPR050274 | Family | Nuclear hormone receptor family NR2 subfamily | Interproscan |
| IPR001723 | Family | Nuclear hormone receptor | Interproscan |
| IPR013088 | Homologous_superfamily | Zinc finger, NHR/GATA-type | Interproscan |
| IPR002347 | Family | Short-chain dehydrogenase/reductase SDR | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR052388 | Family | Peroxisomal trans-2-enoyl-CoA reductase | Interproscan |
| IPR013783 | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR036238 | Homologous_superfamily | Transglutaminase, C-terminal domain superfamily | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR019137 | Family | Nck-associated protein 1 | Interproscan |
| IPR000305 | Domain | GIY-YIG endonuclease | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12474 | P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN | Interproscan |
| PTHR45913 | EPM2A-INTERACTING PROTEIN 1 | Interproscan |
| PTHR24083 | NUCLEAR HORMONE RECEPTOR | Interproscan |
| PTHR24317 | PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR19446 | REVERSE TRANSCRIPTASES | Interproscan |
| PTHR21301 | REVERSE TRANSCRIPTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0016239 | Biological Process | positive regulation of macroautophagy | Interproscan |
| GO:0016684 | Molecular Function | oxidoreductase activity, acting on peroxide as acceptor | Interproscan |
| GO:0070728 | Molecular Function | L-leucine binding | Interproscan |
| GO:0071233 | Biological Process | cellular response to L-leucine | Interproscan |
| GO:1901031 | Biological Process | regulation of response to reactive oxygen species | Interproscan |
| GO:1904262 | Biological Process | negative regulation of TORC1 signaling | Interproscan |
| GO:1990253 | Biological Process | cellular response to leucine starvation | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0043565 | Molecular Function | sequence-specific DNA binding | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0004879 | Molecular Function | nuclear receptor activity | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0030154 | Biological Process | cell differentiation | Interproscan |
| GO:0048856 | Biological Process | anatomical structure development | Interproscan |
| GO:0005777 | Cellular Component | peroxisome | Interproscan |
| GO:0019166 | Molecular Function | trans-2-enoyl-CoA reductase (NADPH) activity | Interproscan |
| GO:0033306 | Biological Process | phytol metabolic process | Interproscan |
| GO:0003810 | Molecular Function | protein-glutamine gamma-glutamyltransferase activity | Interproscan |
| GO:0018149 | Biological Process | peptide cross-linking | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K22756 | NSMCE2, NSE2; E3 SUMO-protein ligase NSE2 | EC:2.3.2.- | DNA repair and recombination proteins | ko03400 | deepkoala |