Genomic Location: scaffold_26:1570044...1578822
NR annotation: XP_015774802.1, PREDICTED: NEDD8-activating enzyme E1 catalytic subunit-like isoform X1 [Acropora digitifera]
Species Acropora hemprichii · all data for this species · gene families
| CDS |
| Ahemp_009100-T1 |
| Transcript |
| Ahemp_009100-T1 |
| Protein |
| Ahemp_009100-T1 |
| UniProt accession | Description |
|---|---|
| Q5R4A0 | NEDD8-activating enzyme E1 catalytic subunit OS=Pongo abelii OX=9601 GN=UBA3 PE=2 SV=2 |
| Q8TBC4 | NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2 |
| Q99MI7 | NEDD8-activating enzyme E1 catalytic subunit OS=Rattus norvegicus OX=10116 GN=Uba3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004328 (this species only) · gene tree & orthology |
| Ubiquitin family | E1|ThiF|ThiF · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08825 all species → | E2_bind | E2 binding domain | Domain | Interproscan |
| PF00899 all species → | ThiF | ThiF family | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR035985 all species → | Homologous_superfamily | Ubiquitin-activating enzyme | Interproscan |
| IPR014929 all species → | Domain | E2 binding | Interproscan |
| IPR030468 all species → | Domain | NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain | Interproscan |
| IPR045886 all species → | Family | ThiF/MoeB/HesA family | Interproscan |
| IPR033127 all species → | Active_site | Ubiquitin-activating enzyme E1, Cys active site | Interproscan |
| IPR000594 all species → | Domain | THIF-type NAD/FAD binding fold | Interproscan |
| IPR023318 all species → | Homologous_superfamily | Ubiquitin activating enzyme, alpha domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10953 all species → | UBIQUITIN-ACTIVATING ENZYME E1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008641 all species → | Molecular Function | ubiquitin-like modifier activating enzyme activity | Interproscan |
| GO:0019781 all species → | Molecular Function | NEDD8 activating enzyme activity | Interproscan |
| GO:0045116 all species → | Biological Process | protein neddylation | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0032446 all species → | Biological Process | protein modification by small protein conjugation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10686 | UBA3, UBE1C; NEDD8-activating enzyme E1 | EC:6.2.1.64 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora hemprichii tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora hemprichii, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
