Genomic Location: chr2:10459088...10511200
NR annotation: XP_048589953.1, serine/threonine-protein kinase atr [Nematostella vectensis]
Species Haliclystus octoradiatus · all data for this species · gene families
| CDS |
| BRAKERHOCT00005005281 |
| Transcript |
| BRAKERHOCT00005005281 |
| Protein |
| BRAKERHOCP00005005281.1 |
| UniProt accession | Description |
|---|---|
| Q13535 | Serine/threonine-protein kinase ATR OS=Homo sapiens OX=9606 GN=ATR PE=1 SV=3 |
| Q9JKK8 | Serine/threonine-protein kinase ATR OS=Mus musculus OX=10090 GN=Atr PE=1 SV=2 |
| Q9DE14 | Serine/threonine-protein kinase atr OS=Xenopus laevis OX=8355 GN=atr PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002088 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00454 all species → | PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | Family | Interproscan |
| PF02260 all species → | FATC | FATC domain | Family | Interproscan |
| PF08064 all species → | UME | UME (NUC010) domain | Domain | Interproscan |
| PF02259 all species → | FAT | FAT domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000403 all species → | Domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Interproscan |
| IPR014009 all species → | Domain | PIK-related kinase | Interproscan |
| IPR011990 all species → | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR003152 all species → | Domain | FATC domain | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR036940 all species → | Homologous_superfamily | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR012993 all species → | Domain | UME domain | Interproscan |
| IPR011989 all species → | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR050517 all species → | Family | DNA Damage Response and Repair Kinase | Interproscan |
| IPR003151 all species → | Domain | PIK-related kinase, FAT | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11139 all species → | ATAXIA TELANGIECTASIA MUTATED ATM -RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0000077 all species → | Biological Process | DNA damage checkpoint signaling | Interproscan |
| GO:0000723 all species → | Biological Process | telomere maintenance | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06640 | ATR; serine/threonine-protein kinase ATR | EC:2.7.11.1 | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Haliclystus octoradiatus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Haliclystus octoradiatus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |