Genomic Location: QPEY01000003.1:3921846...3945050
NR annotation: XP_012554042.1, serine/threonine-protein kinase mTOR [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families
| CDS |
| BRAKERKRET00000001197 |
| Transcript |
| BRAKERKRET00000001197 |
| Protein |
| BRAKERKREP00000001197.1 |
| UniProt accession | Description |
|---|---|
| P42346 | Serine/threonine-protein kinase mTOR OS=Rattus norvegicus OX=10116 GN=Mtor PE=1 SV=1 |
| Q9JLN9 | Serine/threonine-protein kinase mTOR OS=Mus musculus OX=10090 GN=Mtor PE=1 SV=2 |
| P42345 | Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003065 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08771 all species → | FRB_dom | FKBP12-rapamycin binding domain | Domain | Interproscan |
| PF11865 all species → | DUF3385 | Domain of unknown function (DUF3385) | Repeat | Interproscan |
| PF00454 all species → | PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | Family | Interproscan |
| PF02259 all species → | FAT | FAT domain | Repeat | Interproscan |
| PF02260 all species → | FATC | FATC domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036738 all species → | Homologous_superfamily | FKBP12-rapamycin binding domain superfamily | Interproscan |
| IPR003152 all species → | Domain | FATC domain | Interproscan |
| IPR011989 all species → | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR009076 all species → | Domain | FKBP12-rapamycin binding domain | Interproscan |
| IPR011990 all species → | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR018936 all species → | Conserved_site | Phosphatidylinositol 3/4-kinase, conserved site | Interproscan |
| IPR024585 all species → | Domain | Serine/threonine-protein kinase mTOR domain | Interproscan |
| IPR000403 all species → | Domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR036940 all species → | Homologous_superfamily | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Interproscan |
| IPR003151 all species → | Domain | PIK-related kinase, FAT | Interproscan |
| IPR026683 all species → | Domain | Serine/threonine-protein kinase TOR, catalytic domain | Interproscan |
| IPR014009 all species → | Domain | PIK-related kinase | Interproscan |
| IPR050517 all species → | Family | DNA Damage Response and Repair Kinase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11139 all species → | ATAXIA TELANGIECTASIA MUTATED ATM -RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0044877 all species → | Molecular Function | protein-containing complex binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0016301 all species → | Molecular Function | kinase activity | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0016242 all species → | Biological Process | negative regulation of macroautophagy | Interproscan |
| GO:0031929 all species → | Biological Process | TOR signaling | Interproscan |
| GO:0031931 all species → | Cellular Component | TORC1 complex | Interproscan |
| GO:0031932 all species → | Cellular Component | TORC2 complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07203 | MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR | EC:2.7.11.1 | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of BRAKERKREP00000001197.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole body | 18 | 18 | 4,569.89 | 10,794.77 | |
| Whole | 6 | 6 | 1,848.83 | 2,042.28 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep1 | 1 | 1 | 1,793.24 | 1,793.24 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep2 | 1 | 1 | 1,763.75 | 1,763.75 | |
| symbioic hydra M9 strain · symbioic hydra rep1 | 1 | 1 | 2,051.16 | 2,051.16 | |
| symbioic hydra M9 strain · symbioic hydra rep2 | 1 | 1 | 2,212.92 | 2,212.92 | |
| unannotated | 1 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM,
StringTie quantification over 29 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.