Genomic Location: QPEY01000003.1:3080340...3099613
NR annotation: XP_047126139.1, inositol 1,4,5-trisphosphate receptor type 1 isoform X2 [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families
| CDS |
| BRAKERKRET00000001389 |
| Transcript |
| BRAKERKRET00000001389 |
| Protein |
| BRAKERKREP00000001389.1 |
| UniProt accession | Description |
|---|---|
| Q9TU34 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 OS=Bos taurus OX=9913 GN=ITPR1 PE=1 SV=1 |
| Q14643 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3 |
| P11881 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 OS=Mus musculus OX=10090 GN=Itpr1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002035 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02815 all species → | MIR | MIR domain | Domain | Interproscan |
| PF08709 all species → | Ins145_P3_rec | Inositol 1,4,5-trisphosphate/ryanodine receptor | Domain | Interproscan |
| PF01365 all species → | RYDR_ITPR | RIH domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016093 all species → | Domain | MIR motif | Interproscan |
| IPR014821 all species → | Domain | Inositol 1,4,5-trisphosphate/ryanodine receptor | Interproscan |
| IPR035910 all species → | Homologous_superfamily | RyR/IP3 receptor binding core, RIH domain superfamily | Interproscan |
| IPR036300 all species → | Homologous_superfamily | Mir domain superfamily | Interproscan |
| IPR000493 all species → | Family | Inositol 1,4,5-trisphosphate receptor | Interproscan |
| IPR000699 all species → | Domain | RIH domain | Interproscan |
| IPR015925 all species → | Family | Ryanodine/Inositol 1,4,5-trisphosphate receptor | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13715 all species → | RYANODINE RECEPTOR AND IP3 RECEPTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005220 all species → | Molecular Function | inositol 1,4,5-trisphosphate-gated calcium channel activity | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0006816 all species → | Biological Process | calcium ion transport | Interproscan |
| GO:0070679 all species → | Molecular Function | inositol 1,4,5 trisphosphate binding | Interproscan |
| GO:0005262 all species → | Molecular Function | calcium channel activity | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0070588 all species → | Biological Process | calcium ion transmembrane transport | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0005789 all species → | Cellular Component | endoplasmic reticulum membrane | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0016529 all species → | Cellular Component | sarcoplasmic reticulum | Interproscan |
| GO:0030667 all species → | Cellular Component | secretory granule membrane | Interproscan |
| GO:0035091 all species → | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0051209 all species → | Biological Process | release of sequestered calcium ion into cytosol | Interproscan |
BRAKERKREP00000001389.1.Transcript abundance of BRAKERKREP00000001389.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole body | 18 | 5 | 1.87 | 9.20 | |
| Whole | 6 | 5 | 2.96 | 3.96 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep1 | 1 | 1 | 2.69 | 2.69 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep2 | 1 | 1 | 3.15 | 3.15 | |
| symbioic hydra M9 strain · symbioic hydra rep1 | 1 | 1 | 1.53 | 1.53 | |
| symbioic hydra M9 strain · symbioic hydra rep2 | 1 | 0 | 0.00 | 0.00 | |
| unannotated | 1 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR21134057 | whole body | whole body | not recorded | not recorded | SRP392977 | 9.20 |
| SRR21134064 | whole body | whole body | not recorded | not recorded | SRP392977 | 8.08 |
| SRR21134055 | whole body | whole body | not recorded | not recorded | SRP392977 | 7.89 |
| SRR21134054 | whole body | whole body | not recorded | not recorded | SRP392977 | 4.92 |
| SRR21134066 | whole body | whole body | not recorded | not recorded | SRP392977 | 3.50 |
| SRR21134050 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134051 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134052 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134053 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134056 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134058 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134059 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134060 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134061 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134062 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134063 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134065 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134067 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR10058803 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.96 |
| SRR10058805 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.74 |
| SRR10058807 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.62 |
| SRR10058804 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.39 |
| SRR10058806 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.03 |
| SRR10058802 | Whole | Whole | not recorded | not recorded | SRP220397 | 0.00 |
| DRR048593 | aposymbioic hydra M9 strain · aposymbioic hydra rep1 | not recorded | not recorded | aposymbioic hydra rep1 | DRP003902 | 2.69 |
| DRR048594 | aposymbioic hydra M9 strain · aposymbioic hydra rep2 | not recorded | not recorded | aposymbioic hydra rep2 | DRP003902 | 3.15 |
| DRR048595 | symbioic hydra M9 strain · symbioic hydra rep1 | not recorded | not recorded | symbioic hydra rep1 | DRP003902 | 1.53 |
| DRR048596 | symbioic hydra M9 strain · symbioic hydra rep2 | not recorded | not recorded | symbioic hydra rep2 | DRP003902 | 0.00 |
| ERR13389755 | unannotated | not recorded | not recorded | not recorded | ERP162636 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM,
StringTie quantification over 29 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Hydra viridissima tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 3 | g15793 | -0.469419971177456 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Hydra viridissima, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
