Gene detail

Detailed information of BRAKERKREP00000001595.1 in Hydra viridissima

Genomic Location: not available for this species
NR annotation: XP_012553835.2, leukotriene A-4 hydrolase [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families

Sequence

CDS

BRAKERKRET00000001595

atGGCTCCTTCAGATATTATTGATCCATGTAGCTTATCAAATATTGATATCTTTCAAATCACACATCTTGACTGGAATATACATGTTGATTTTGAATCACAGAAATTATCATGTACAGCTGTTCAAAGCTTTAAATGCCTTAAGGATGATTACGATAAGCTAatTCTTGATACAAATCAATTGAACATTGAAGCTGTTTTCTATAATGATAAAGTTGCACCTTTTGTAATCTTACCCTCTGTGAAACCATTTGGTGAACCACTTGAAATTACTATACCATCAAgcaaaatagGATCAGAgtttacaattacaataaacTACCACACATCTTCAACAGCACATGCATTGCAGTGGTTAAAACCAGAGCAAACTCTTGGACAAGTATACCCCTACATGTTTACTCAATGTCAGGCAATACATGCTCGAAGTTTGCTTCCTTGTCAAGATTCTCCATGCCATAAGTTTACCTATTCTTCTAAGGTTACAGTTCCAGTAGAGTTGGTTGCATTAATGAGTGCAGTAAAAGGTGGTGAAgtcattttagaaaataataagaaagaatatcattttcatcaaaagaTATGCATACCATCATATCTTCTAGCAATTGTAGTTGGTGCATTAGAGTTTCgTAATGTTGGTCCCCGATCAAAGGTTTGGTGTGAAATGCCAATGATTGAAGAATGTGCTTTTGAATTTGCAAAGGTTGAAGACATGTTAAAAGCTGGTGAACTATTGATGGGACCTTATGTTTGGGAACAGTATGATATTCTTGTACTTCCTCCTTCTTTTCCTTATGGTGGAATGGAAAATCCTTGTTTGACCTTTGTCACCCCTACTGTTGtaGTTGGTGATCGCTCTCTGACAGCGGTAATAGCACATGAGATCACACACAGCTGGACAGGAAATCTTGTTACTAACAAAACTTGGGAACATTTCTGgcTAAATGAAGGGTTCACTCGATTTTTGGAGGGGAAAATTGTTGGATTATTAGATGGGGAGTCTACTCGACAATTCATGGCTAttgAAGGTTGGAGTCATTTACATGATTCGgTTGAGGTTTTTggaaaagataataaattgACTGCATTACAACCTGCTTTGAATGGAGTTGATCCTGATGATTCATTTTCTAGTGTTCCTTATGAGAAAGGATATGCTTTTCTTTACTTCATAGAGCATCTGGTAGGAGGTCCTgatgtatgtaatattttcCTACGAAAGTATATTGACAAGTTCAAATATACAAGTATAGTTACAGATGAtttcaaagaatttctttGTGAATATTTTAAGGAACAGCTGGATTTAACATCTGCAATTGATTGGGATGCTTGGCTTCATTCCCCTGGCATGCCACCTGTTCAAATCATTGACATGTATGATCAAACATTGGCAATTGTTTGCAAGGAGTTAGCTGATAAGTGGACCGTcGCTTCATGTACTGGAAATTTTTGCGATTTTTCTGAAGAGGAATTTACATCATTCactgttttgcaaaaaattgaCTTCCTTACAAAATTGTATCAAACAactACGTTGTCCTTACCAGCTGTTAAAGCGCTATCGGATATTtacaaactttcaaattataaaaacacggAAATAAAGTTTGCTTTCCTTCGTTTATGCATTCGATCAAAATGGAGTGAGCGTTACAACGATGtcgtaaaatttcttttacagcAAGGTCGTATGAAGTTCGTCAGACCTCTATATAGGGAAATGTACAAAAATGACGAAGCAAAGAGTTTGGCTATTGAAACGTTTAAACGACATCGACACGTTTACCATTCCATAACTTCTACGATGacaACGTTGTCCTTACCAGCTGTTAAAGCGCTATCGGATATTtacaaactttcaaattataaaaacacggAAATAAAGTTTGCTTTCCTTCGTTTATGCATCCGATCAAAATGGAGTGAGCGTTACAACGATGtcgtaaaatttcttttacagcAAGGTCGTATGAAGTTCGTCAGACCTCTATATAGGGAAATGTACAAAAATGACGAAGCAAAGAGTTTGGCTATTGAAACGTTTAAACGACATCGACACGTTTACCATTCCATAACTTCTACGATGGTGAGTAAAGACCTCCATTTGTGTGTGGAGAAttaa

Transcript

BRAKERKRET00000001595

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6IP81	Leukotriene A-4 hydrolase OS=Xenopus laevis OX=8355 GN=lta4h.L PE=1 SV=1
Q3SZH7	Leukotriene A-4 hydrolase OS=Bos taurus OX=9913 GN=LTA4H PE=2 SV=3
P09960	Leukotriene A-4 hydrolase OS=Homo sapiens OX=9606 GN=LTA4H PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004565 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01433 all species →	Peptidase_M1	Peptidase family M1 domain	Domain	Interproscan
PF17900 all species →	Peptidase_M1_N	Peptidase M1 N-terminal domain	Domain	Interproscan
PF09127 all species →	Leuk-A4-hydro_C	Leukotriene A4 hydrolase, C-terminal	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR042097 all species →	Homologous_superfamily	Aminopeptidase N-like , N-terminal domain superfamliy	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR001930 all species →	Family	Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase	Interproscan
IPR014782 all species →	Domain	Peptidase M1, membrane alanine aminopeptidase	Interproscan
IPR027268 all species →	Homologous_superfamily	Peptidase M4/M1, CTD superfamily	Interproscan
IPR045357 all species →	Domain	Aminopeptidase N-like , N-terminal domain	Interproscan
IPR034015 all species →	Family	Aminopeptidase, leukotriene A4 hydrolase-like	Interproscan
IPR015211 all species →	Domain	Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal	Interproscan
IPR049980 all species →	Domain	Leukotriene A4 hydrolase-like, catalytic domain	Interproscan
IPR038502 all species →	Homologous_superfamily	Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45726 all species →	LEUKOTRIENE A-4 HYDROLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0004177 all species →	Molecular Function	aminopeptidase activity	Interproscan
GO:0004301 all species →	Molecular Function	epoxide hydrolase activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0043171 all species →	Biological Process	peptide catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01254	LTA4H; leukotriene-A4 hydrolase	EC:3.3.2.6	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of BRAKERKREP00000001595.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

29Samples

10TPM > 0

7Conditions

31.6Max TPM

4.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole body	18	2	2.24	31.65
Whole	6	5	11.15	15.57
aposymbioic hydra M9 strain · aposymbioic hydra rep1	1	1	11.55	11.55
aposymbioic hydra M9 strain · aposymbioic hydra rep2	1	1	12.55	12.55
symbioic hydra M9 strain · symbioic hydra rep1	1	1	11.39	11.39
symbioic hydra M9 strain · symbioic hydra rep2	1	0	0.00	0.00
unannotated	1	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR21134056	whole body	whole body	not recorded	not recorded	SRP392977	31.65
SRR21134060	whole body	whole body	not recorded	not recorded	SRP392977	8.72
SRR21134050	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134051	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134052	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134053	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134054	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134055	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134057	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134058	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134059	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134061	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134062	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134063	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134064	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134065	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134066	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134067	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR10058807	Whole	Whole	not recorded	not recorded	SRP220397	15.57
SRR10058803	Whole	Whole	not recorded	not recorded	SRP220397	13.92
SRR10058806	Whole	Whole	not recorded	not recorded	SRP220397	13.84
SRR10058804	Whole	Whole	not recorded	not recorded	SRP220397	12.45
SRR10058805	Whole	Whole	not recorded	not recorded	SRP220397	11.13
SRR10058802	Whole	Whole	not recorded	not recorded	SRP220397	0.00
DRR048593	aposymbioic hydra M9 strain · aposymbioic hydra rep1	not recorded	not recorded	aposymbioic hydra rep1	DRP003902	11.55
DRR048594	aposymbioic hydra M9 strain · aposymbioic hydra rep2	not recorded	not recorded	aposymbioic hydra rep2	DRP003902	12.55
DRR048595	symbioic hydra M9 strain · symbioic hydra rep1	not recorded	not recorded	symbioic hydra rep1	DRP003902	11.39
DRR048596	symbioic hydra M9 strain · symbioic hydra rep2	not recorded	not recorded	symbioic hydra rep2	DRP003902	0.00
ERR13389755	unannotated	not recorded	not recorded	not recorded	ERP162636	0.00

Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM, StringTie quantification over 29 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.