Gene detail

Detailed information of BRAKERKREP00000004591.1 in Hydra viridissima

Genomic Location: not available for this species
NR annotation: XP_047146478.1, ER degradation-enhancing alpha-mannosidase-like protein 1 [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q92611	ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Homo sapiens OX=9606 GN=EDEM1 PE=1 SV=1
Q925U4	ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Mus musculus OX=10090 GN=Edem1 PE=1 SV=1
O94726	ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mnl1 PE=3 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004477 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01532 all species →	Glyco_hydro_47	Glycosyl hydrolase family 47	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036026 all species →	Homologous_superfamily	Seven-hairpin glycosidases	Interproscan
IPR012341 all species →	Homologous_superfamily	Six-hairpin glycosidase-like superfamily	Interproscan
IPR044674 all species →	Family	ER degradation-enhancing alpha-mannosidase-like protein 1/2/3	Interproscan
IPR001382 all species →	Family	Glycoside hydrolase family 47	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45679 all species →	ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004571 all species →	Molecular Function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:1904380 all species →	Biological Process	endoplasmic reticulum mannose trimming	Interproscan
GO:1904382 all species →	Biological Process	mannose trimming involved in glycoprotein ERAD pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10084	EDEM1; ER degradation enhancer, mannosidase alpha-like 1	-	Lectins	ko04091	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of BRAKERKREP00000004591.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

29Samples

21TPM > 0

7Conditions

186.3Max TPM

40.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole body	18	11	37.20	186.33
Whole	6	6	58.43	67.88
aposymbioic hydra M9 strain · aposymbioic hydra rep1	1	1	36.01	36.01
aposymbioic hydra M9 strain · aposymbioic hydra rep2	1	1	41.69	41.69
symbioic hydra M9 strain · symbioic hydra rep1	1	1	34.60	34.60
symbioic hydra M9 strain · symbioic hydra rep2	1	1	50.36	50.36
unannotated	1	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR21134065	whole body	whole body	not recorded	not recorded	SRP392977	186.33
SRR21134054	whole body	whole body	not recorded	not recorded	SRP392977	86.26
SRR21134055	whole body	whole body	not recorded	not recorded	SRP392977	71.32
SRR21134060	whole body	whole body	not recorded	not recorded	SRP392977	64.34
SRR21134056	whole body	whole body	not recorded	not recorded	SRP392977	62.63
SRR21134057	whole body	whole body	not recorded	not recorded	SRP392977	62.63
SRR21134064	whole body	whole body	not recorded	not recorded	SRP392977	60.77
SRR21134066	whole body	whole body	not recorded	not recorded	SRP392977	59.45
SRR21134050	whole body	whole body	not recorded	not recorded	SRP392977	7.55
SRR21134053	whole body	whole body	not recorded	not recorded	SRP392977	6.67
SRR21134052	whole body	whole body	not recorded	not recorded	SRP392977	1.61
SRR21134051	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134058	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134059	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134061	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134062	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134063	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134067	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR10058802	Whole	Whole	not recorded	not recorded	SRP220397	67.88
SRR10058804	Whole	Whole	not recorded	not recorded	SRP220397	62.14
SRR10058805	Whole	Whole	not recorded	not recorded	SRP220397	58.80
SRR10058803	Whole	Whole	not recorded	not recorded	SRP220397	54.88
SRR10058806	Whole	Whole	not recorded	not recorded	SRP220397	54.30
SRR10058807	Whole	Whole	not recorded	not recorded	SRP220397	52.59
DRR048593	aposymbioic hydra M9 strain · aposymbioic hydra rep1	not recorded	not recorded	aposymbioic hydra rep1	DRP003902	36.01
DRR048594	aposymbioic hydra M9 strain · aposymbioic hydra rep2	not recorded	not recorded	aposymbioic hydra rep2	DRP003902	41.69
DRR048595	symbioic hydra M9 strain · symbioic hydra rep1	not recorded	not recorded	symbioic hydra rep1	DRP003902	34.60
DRR048596	symbioic hydra M9 strain · symbioic hydra rep2	not recorded	not recorded	symbioic hydra rep2	DRP003902	50.36
ERR13389755	unannotated	not recorded	not recorded	not recorded	ERP162636	0.00

Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM, StringTie quantification over 29 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.