Genomic Location: not available for this species
NR annotation: XP_002157214.1, dihydrofolate reductase [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families
| CDS |
| BRAKERKRET00000012164 |
| Transcript |
| BRAKERKRET00000012164 |
| Protein |
| BRAKERKREP00000012164.1 |
| UniProt accession | Description |
|---|---|
| P09503 | Viral dihydrofolate reductase OS=Saimiriine herpesvirus 2 (strain 11) OX=10383 GN=DHFR PE=3 SV=1 |
| Q05762 | Bifunctional dihydrofolate reductase-thymidylate synthase 1 OS=Arabidopsis thaliana OX=3702 GN=THY-1 PE=1 SV=2 |
| P51820 | Bifunctional dihydrofolate reductase-thymidylate synthase OS=Glycine max OX=3847 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002484 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 all species → | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001796 all species → | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR024072 all species → | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| IPR012259 all species → | Family | Dihydrofolate reductase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48069 all species → | DIHYDROFOLATE REDUCTASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004146 all species → | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 all species → | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0046452 all species → | Biological Process | dihydrofolate metabolic process | Interproscan |
| GO:0046655 all species → | Biological Process | folic acid metabolic process | Interproscan |
| GO:0050661 all species → | Molecular Function | NADP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00287 | DHFR, folA; dihydrofolate reductase | EC:1.5.1.3 | Antifolate resistance | ko01523 | deepkoala |
Transcript abundance of BRAKERKREP00000012164.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole body | 18 | 0 | 0.00 | 0.00 | |
| Whole | 6 | 3 | 0.15 | 0.38 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep1 | 1 | 1 | 0.76 | 0.76 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep2 | 1 | 0 | 0.00 | 0.00 | |
| symbioic hydra M9 strain · symbioic hydra rep1 | 1 | 0 | 0.00 | 0.00 | |
| symbioic hydra M9 strain · symbioic hydra rep2 | 1 | 0 | 0.00 | 0.00 | |
| unannotated | 1 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM,
StringTie quantification over 29 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.