Gene detail

Detailed information of BRAKERKREP00000022762.1 in Hydra viridissima

Genomic Location: QPEY01000524.1:623667...624512
NR annotation: WP_012251586.1, methylenetetrahydrofolate reductase [NAD(P)H] [Bordetella petrii]
Species Hydra viridissima · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O67422	5,10-methylenetetrahydrofolate reductase OS=Aquifex aeolicus (strain VF5) OX=224324 GN=metF PE=3 SV=1
P0AEZ1	5,10-methylenetetrahydrofolate reductase OS=Escherichia coli (strain K12) OX=83333 GN=metF PE=1 SV=1
P11003	5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=metF PE=3 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0024589 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02219 all species →	MTHFR	Methylenetetrahydrofolate reductase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003171 all species →	Family	Methylenetetrahydrofolate reductase-like	Interproscan
IPR029041 all species →	Homologous_superfamily	FAD-linked oxidoreductase-like	Interproscan
IPR004620 all species →	Family	5,10-methylenetetrahydrofolate reductase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45754 all species →	METHYLENETETRAHYDROFOLATE REDUCTASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004489 all species →	Molecular Function	methylenetetrahydrofolate reductase (NAD(P)H) activity	Interproscan
GO:0006555 all species →	Biological Process	methionine metabolic process	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0009086 all species →	Biological Process	methionine biosynthetic process	Interproscan
GO:0035999 all species →	Biological Process	tetrahydrofolate interconversion	Interproscan
GO:0071949 all species →	Molecular Function	FAD binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00297	metF, MTHFR; methylenetetrahydrofolate reductase (NADH)	EC:1.5.1.54	One carbon pool by folate	ko00670	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of BRAKERKREP00000022762.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

29Samples

8TPM > 0

7Conditions

6.5Max TPM

1.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole body	18	0	0.00	0.00
Whole	6	5	4.70	6.51
aposymbioic hydra M9 strain · aposymbioic hydra rep1	1	1	3.95	3.95
aposymbioic hydra M9 strain · aposymbioic hydra rep2	1	1	3.14	3.14
symbioic hydra M9 strain · symbioic hydra rep1	1	1	2.91	2.91
symbioic hydra M9 strain · symbioic hydra rep2	1	0	0.00	0.00
unannotated	1	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR21134050	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134051	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134052	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134053	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134054	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134055	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134056	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134057	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134058	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134059	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134060	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134061	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134062	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134063	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134064	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134065	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134066	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134067	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR10058804	Whole	Whole	not recorded	not recorded	SRP220397	6.51
SRR10058805	Whole	Whole	not recorded	not recorded	SRP220397	5.78
SRR10058807	Whole	Whole	not recorded	not recorded	SRP220397	5.56
SRR10058803	Whole	Whole	not recorded	not recorded	SRP220397	5.47
SRR10058806	Whole	Whole	not recorded	not recorded	SRP220397	4.88
SRR10058802	Whole	Whole	not recorded	not recorded	SRP220397	0.00
DRR048593	aposymbioic hydra M9 strain · aposymbioic hydra rep1	not recorded	not recorded	aposymbioic hydra rep1	DRP003902	3.95
DRR048594	aposymbioic hydra M9 strain · aposymbioic hydra rep2	not recorded	not recorded	aposymbioic hydra rep2	DRP003902	3.14
DRR048595	symbioic hydra M9 strain · symbioic hydra rep1	not recorded	not recorded	symbioic hydra rep1	DRP003902	2.91
DRR048596	symbioic hydra M9 strain · symbioic hydra rep2	not recorded	not recorded	symbioic hydra rep2	DRP003902	0.00
ERR13389755	unannotated	not recorded	not recorded	not recorded	ERP162636	0.00

Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM, StringTie quantification over 29 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.