Genomic Location: QPEY01000524.1:1940468...1942957
NR annotation: WP_103275068.1, endopeptidase La [Achromobacter sp. AONIH1]
Species Hydra viridissima · all data for this species · gene families
| CDS |
| BRAKERKRET00000022891 |
| Transcript |
| BRAKERKRET00000022891 |
| Protein |
| BRAKERKREP00000022891.1 |
| UniProt accession | Description |
|---|---|
| P74956 | Lon protease OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=lon PE=3 SV=2 |
| P0A9M1 | Lon protease OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=lon PE=3 SV=1 |
| P0A9M0 | Lon protease OS=Escherichia coli (strain K12) OX=83333 GN=lon PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001331 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00004 all species → | AAA | ATPase family associated with various cellular activities (AAA) | Domain | Interproscan |
| PF02190 all species → | LON_substr_bdg | ATP-dependent protease La (LON) substrate-binding domain | Family | Interproscan |
| PF05362 all species → | Lon_C | Lon protease (S16) C-terminal proteolytic domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003959 all species → | Domain | ATPase, AAA-type, core | Interproscan |
| IPR003111 all species → | Domain | Lon protease, N-terminal domain | Interproscan |
| IPR004815 all species → | Family | Lon protease, bacterial/eukaryotic-type | Interproscan |
| IPR014721 all species → | Homologous_superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Interproscan |
| IPR046336 all species → | Homologous_superfamily | Lon protease, N-terminal domain superfamily | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR008269 all species → | Domain | Peptidase S16, Lon proteolytic domain | Interproscan |
| IPR027543 all species → | Family | Lon protease, bacterial | Interproscan |
| IPR003593 all species → | Domain | AAA+ ATPase domain | Interproscan |
| IPR008268 all species → | Active_site | Peptidase S16, active site | Interproscan |
| IPR027065 all species → | Family | Lon protease | Interproscan |
| IPR015947 all species → | Homologous_superfamily | PUA-like superfamily | Interproscan |
| IPR020568 all species → | Homologous_superfamily | Ribosomal protein uS5 domain 2-type superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10046 all species → | ATP DEPENDENT LON PROTEASE FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0004176 all species → | Molecular Function | ATP-dependent peptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0004252 all species → | Molecular Function | serine-type endopeptidase activity | Interproscan |
| GO:0043565 all species → | Molecular Function | sequence-specific DNA binding | Interproscan |
| GO:0030163 all species → | Biological Process | protein catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01338 | lon; ATP-dependent Lon protease | EC:3.4.21.53 | Peptidases and inhibitors | ko01002 | deepkoala |
Transcript abundance of BRAKERKREP00000022891.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole body | 18 | 1 | 0.03 | 0.61 | |
| Whole | 6 | 6 | 1.47 | 3.72 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep1 | 1 | 1 | 0.01 | 0.01 | |
| aposymbioic hydra M9 strain · aposymbioic hydra rep2 | 1 | 1 | 0.51 | 0.51 | |
| symbioic hydra M9 strain · symbioic hydra rep1 | 1 | 1 | 0.24 | 0.24 | |
| symbioic hydra M9 strain · symbioic hydra rep2 | 1 | 0 | 0.00 | 0.00 | |
| unannotated | 1 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR21134060 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.61 |
| SRR21134050 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134051 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134052 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134053 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134054 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134055 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134056 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134057 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134058 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134059 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134061 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134062 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134063 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134064 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134065 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134066 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR21134067 | whole body | whole body | not recorded | not recorded | SRP392977 | 0.00 |
| SRR10058802 | Whole | Whole | not recorded | not recorded | SRP220397 | 3.72 |
| SRR10058804 | Whole | Whole | not recorded | not recorded | SRP220397 | 1.42 |
| SRR10058805 | Whole | Whole | not recorded | not recorded | SRP220397 | 1.11 |
| SRR10058803 | Whole | Whole | not recorded | not recorded | SRP220397 | 0.99 |
| SRR10058806 | Whole | Whole | not recorded | not recorded | SRP220397 | 0.94 |
| SRR10058807 | Whole | Whole | not recorded | not recorded | SRP220397 | 0.61 |
| DRR048593 | aposymbioic hydra M9 strain · aposymbioic hydra rep1 | not recorded | not recorded | aposymbioic hydra rep1 | DRP003902 | 0.01 |
| DRR048594 | aposymbioic hydra M9 strain · aposymbioic hydra rep2 | not recorded | not recorded | aposymbioic hydra rep2 | DRP003902 | 0.51 |
| DRR048595 | symbioic hydra M9 strain · symbioic hydra rep1 | not recorded | not recorded | symbioic hydra rep1 | DRP003902 | 0.24 |
| DRR048596 | symbioic hydra M9 strain · symbioic hydra rep2 | not recorded | not recorded | symbioic hydra rep2 | DRP003902 | 0.00 |
| ERR13389755 | unannotated | not recorded | not recorded | not recorded | ERP162636 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM,
StringTie quantification over 29 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Hydra viridissima tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 14 | g2286 | 0.992583301302037 |
| Negatively correlated | 3 | g7763 | -0.491620639198961 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Hydra viridissima, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
