Gene detail

Detailed information of BRAKERKREP00000024916.1 in Hydra viridissima

Genomic Location: not available for this species
NR annotation: XP_047140084.1, ubiquitin-like modifier-activating enzyme 6 isoform X2 [Hydra vulgaris]
Species Hydra viridissima · all data for this species · gene families

Sequence

CDS

BRAKERKRET00000024916

ATGGcaacaaataataaagatgAAATTGATGATTCCCTTTACAGTCGACAGCGGTATGTACTTGGTGACAATGCTATGCAAAAACTTGCAAAAGCAAATGTCCTTCTTTCTGGGTTAGGAGGACTAGGTGTTGAAATTGcaaagaaTGTGATCTTGGCTGGTGTGAATTCGCTTACTCtacttgatgaaaaaatatgcaCTGAAGTAGATCTTGGAACACAGTTTTTCTTGACGCAGCAAGATGTAAATGATAAACTTTCAAGAGCATCAGCCTGCAGGGCGAGACTTGCTGAGTTAAATCCACATGTTACAGTAAAGATTGTTCATGATGACATTCTCAATAATCTTGATTATTTAAAGGCTTATCAGTGTGTTGTAATAACTGAAATGCCATTTTCTGATCAAATTGTTCTGAACAATTTTTGTCGGCAACAAGAACCAGCTATTTATtttataTCTGGTGATGTCCGTGGATTGTTTAGCTATGCCTTTTGTGATTTTGGCAAAAAGTTTGAAGTAGTTGATGTTGATGGAGAGGAATACAGAGAAGTATTCATTGGATCTATTACCAAGtcCAACCCAGCAATAGTTGGTACACTTGAAAATAGACTACATGGATTACAAACTGGTGACAGAGTTCTACTAAAAGATATCAATGGCATGTCAGCACTTAATGATAACACATTTCTAGTTCAATATTTAACCCCGTATACTTTCACTATCAATTGTGATACTTCAAATGatgagtttaaaatatatgaacaCGGTGGTgtgttttgcaaaataaaaacaccaaGCATAATGACTTTTGAAAGTTTAGAGATACAAATTACTAAGCCTAGCATTATATTAAGtgatttatcaaaattggAATCCCCATTGCAAATTCTACTtgcttttcaaagtttttacaaatatattttacaaaagaaatcattaaGTGACCTTTCAAAAGACTTTGATTTGTTGCATAGTATTGCAGTAGACATAGATAAGGAGGGTACTAATgttgagattttaaaattattttctaaaactgGGAGTGTTGTATTTGCTCCTTTATGTGCTATTATTGGAGGTATTATTTCACAAGAAGTTCTTAAGAGTCTTACTGGAAAGTTTACAccactttttcagttttttgttcTAGATGCTATGGAACTAGCAGATAGAAATGATAGAGTAGAACATCCATACAATAGATACTTCTCTTTAAATATGTGTTTAAGTTCAGATTTAGTTGGAAAGTTATCACATTTGTCTTTATTTATGGTGGGATGTGGTGCAATTGGTTGTGAGTTGTTAAAGAACTTTGCATTAGTTGGCTTGTCGACAAAAGGTGATAGTATGATGACCATCACTGACAatgatttaattgaaaaatctaaTCTTAATCGACAGTTTCTCTTTCGGCCATGGCACATTCAACAACCTAAGTCAGTTATTGCATCAAAACAAGTACACGAGATTAATCCAGAAATGAAGATTGATGCACACCAaaggaaaaTTTCAATCGATAcagaaaatatatacaatgatcatttctttcaaaaacataatattattgtaaatgCTTTGGATAATATTGAAACAAGAAGATATATAGATGGGAGGTGTGTCTCCAATACCCGACCACTGATTGAAACAGGCACCATGGGAACGAAAGGTCATGTTCAGGTGGTAGTGCCTCATGTAACAGAGACTTATTCAAGtcagCGTGATCCTGTTGATGAAGATGTACCCTATTGTACCCTGAAGTCATTCCCTCAGCAGATTGAGCATACCATTCAATGGGCAAGAGACaagTTTGATAGCTTGTTCACATATAAACCtgaaatatacaataaattttggGAGAAAAATAAAGACCATTATCAGATTGTTAAGaattttcaagaaaattatcAGTTTCCTGATGGCTTTGTTGTATCTGTAACACTGTTAAGAAAAAAGCCACTAAATTATGAATGTTGTGTTAAAGAAGGCTACCTCAGGTTTCacagttatttttataataagGCTTTACAATTGCTTAATGCTTTTCCACTTGACACAAAGTTAGCAGATGGATCTTGGTTTTGGCAGTCTCCAAAAAAACCACCTTCTCCAATTCAATTTGATATACAGAATCCATTGCACATGCAATTTGTGACAAGCTATGCCATGTTACTCTCAAAAGTATTTGGAGTTTGGAATGAGgATTGCAGAAGTGTTAGCATTTCTGATATCATTAATTCAATAAAGTTGCCAGAGTTTAAGCCATCAAAGAAGGAAGTTGTAACTGAAGAGAGCCAGAacaaagagaataaaaaagagaatttggACAAAGTTGGTGATCTTGTCCAGTATTTGACTTCATTGAAAGAATTAAATGccaaaGAATTGTCTAtagaacattttgaaaaagacaatGATTATAATGgtcatttagattttattgTAGCTACATCtAATTTGCGAGCTACAATGTATGGGATTGAGAATGCTGACcgttataaaattaaaagaattgctGGAAGGATTATTCCTGCCATTGCAACAACAACGTCTGTGATTGCTGGGTTGGCTACAATAGAATTGCTAAAAGTAGTTGCTGGAAGCTCTcaagataatttaaagaattgttttttgaatcttGCCATTCCATTGATAGTTTTGTCTGAACCTGCACCTGctccaaaaacaaaaattatagATGGTGTGGAGTTTACATGCTGGGATAGATGGGATGTCTATGGGgataaagaatataaattaaaagaccttattgatcattttaaaaAAAAATGTGGCCTTACAGTGAACATGGTATGTCAAGGTTTAAAGATGATCTACATTCCTTTCATGCCTGGGCATACAAAGCGTGTGAATTACTTaatgactGAACTTTTGAAGCCTGGAAAAGATATTCTATACGCCGATATTATTATTGGATTTCAAAATccagatttaaatttagaggATGACCTGCCAGCTCCTCCAGTTcgatattttttcaacaatttaagGAATTGA

Transcript

BRAKERKRET00000024916

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A0AVT1	Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens OX=9606 GN=UBA6 PE=1 SV=1
Q8C7R4	Ubiquitin-like modifier-activating enzyme 6 OS=Mus musculus OX=10090 GN=Uba6 PE=1 SV=1
Q29504	Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus cuniculus OX=9986 GN=UBA1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001434 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF09358 all species →	E1_UFD	Ubiquitin fold domain	Domain	Interproscan
PF16190 all species →	E1_FCCH	Ubiquitin-activating enzyme E1 FCCH domain	Domain	Interproscan
PF00899 all species →	ThiF	ThiF family	Domain	Interproscan
PF10585 all species →	UBA_E1_SCCH	Ubiquitin-activating enzyme, SCCH domain	Domain	Interproscan
PF16191 all species →	E1_4HB	Ubiquitin-activating enzyme E1 four-helix bundle	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR038252 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, C-terminal domain superfamily	Interproscan
IPR035985 all species →	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR000011 all species →	Family	Ubiquitin/SUMO-activating enzyme E1-like	Interproscan
IPR042063 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, SCCH domain	Interproscan
IPR018965 all species →	Domain	Ubiquitin-activating enzyme E1, C-terminal	Interproscan
IPR032418 all species →	Domain	Ubiquitin-activating enzyme E1, FCCH domain	Interproscan
IPR042449 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1	Interproscan
IPR000594 all species →	Domain	THIF-type NAD/FAD binding fold	Interproscan
IPR042302 all species →	Homologous_superfamily	Ubiquitin-activating enzyme E1, FCCH domain superfamily	Interproscan
IPR019572 all species →	Domain	Ubiquitin-activating enzyme, SCCH domain	Interproscan
IPR045886 all species →	Family	ThiF/MoeB/HesA family	Interproscan
IPR018075 all species →	Family	Ubiquitin-activating enzyme E1	Interproscan
IPR032420 all species →	Domain	Ubiquitin-activating enzyme E1, four-helix bundle	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953 all species →	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008641 all species →	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan
GO:0036211 all species →	Biological Process	protein modification process	Interproscan
GO:0004839 all species →	Molecular Function	ubiquitin activating enzyme activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006511 all species →	Biological Process	ubiquitin-dependent protein catabolic process	Interproscan
GO:0006974 all species →	Biological Process	DNA damage response	Interproscan
GO:0016567 all species →	Biological Process	protein ubiquitination	Interproscan
GO:0019780 all species →	Molecular Function	FAT10 activating enzyme activity	Interproscan
GO:0032446 all species →	Biological Process	protein modification by small protein conjugation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10699	UBE1L2, UBA6; ubiquitin-activating enzyme E1-like protein 2	EC:6.2.1.45	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of BRAKERKREP00000024916.1 across 29 RNA-seq samples of Hydra viridissima. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

29Samples

7TPM > 0

7Conditions

0.2Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole body	18	1	0.01	0.15
Whole	6	3	0.07	0.25
aposymbioic hydra M9 strain · aposymbioic hydra rep1	1	1	0.01	0.01
aposymbioic hydra M9 strain · aposymbioic hydra rep2	1	1	0.24	0.24
symbioic hydra M9 strain · symbioic hydra rep1	1	1	0.03	0.03
symbioic hydra M9 strain · symbioic hydra rep2	1	0	0.00	0.00
unannotated	1	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR21134064	whole body	whole body	not recorded	not recorded	SRP392977	0.15
SRR21134050	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134051	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134052	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134053	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134054	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134055	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134056	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134057	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134058	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134059	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134060	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134061	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134062	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134063	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134065	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134066	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR21134067	whole body	whole body	not recorded	not recorded	SRP392977	0.00
SRR10058803	Whole	Whole	not recorded	not recorded	SRP220397	0.25
SRR10058807	Whole	Whole	not recorded	not recorded	SRP220397	0.14
SRR10058806	Whole	Whole	not recorded	not recorded	SRP220397	0.06
SRR10058802	Whole	Whole	not recorded	not recorded	SRP220397	0.00
SRR10058804	Whole	Whole	not recorded	not recorded	SRP220397	0.00
SRR10058805	Whole	Whole	not recorded	not recorded	SRP220397	0.00
DRR048593	aposymbioic hydra M9 strain · aposymbioic hydra rep1	not recorded	not recorded	aposymbioic hydra rep1	DRP003902	0.01
DRR048594	aposymbioic hydra M9 strain · aposymbioic hydra rep2	not recorded	not recorded	aposymbioic hydra rep2	DRP003902	0.24
DRR048595	symbioic hydra M9 strain · symbioic hydra rep1	not recorded	not recorded	symbioic hydra rep1	DRP003902	0.03
DRR048596	symbioic hydra M9 strain · symbioic hydra rep2	not recorded	not recorded	symbioic hydra rep2	DRP003902	0.00
ERR13389755	unannotated	not recorded	not recorded	not recorded	ERP162636	0.00

Source: CnidoSite RNA-seq expression matrices (HVIRI_TPM, StringTie quantification over 29 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.