Genomic Location: :...
NR annotation: XP_047135257.1, E3 ubiquitin-protein ligase Itchy isoform X2 [Hydra vulgaris]
| CDS | ||||
| BRAKERKYLT00000021493 | ||||
| Transcript |
| BRAKERKYLT00000021493 |
| Protein |
| BRAKERKYLP00000021493.1 |
| Uniprot term | Description | |||
|---|---|---|---|---|
| Q8C863 | E3 ubiquitin-protein ligase Itchy OS=Mus musculus OX=10090 GN=Itch PE=1 SV=2 | |||
| Q96J02 | E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2 | |||
| Q8BZZ3 | NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus OX=10090 GN=Wwp1 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00397 | WW | WW domain | Domain | Interproscan |
| PF00536 | SAM_1 | SAM domain (Sterile alpha motif) | Domain | Interproscan |
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00168 | C2 | C2 domain | Domain | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF00023 | Ank | Ankyrin repeat | Repeat | Interproscan |
| PF13637 | Ank_4 | Ankyrin repeats (many copies) | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001202 | Domain | WW domain | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR001660 | Domain | Sterile alpha motif domain | Interproscan |
| IPR000008 | Domain | C2 domain | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR013761 | Homologous_superfamily | Sterile alpha motif/pointed domain superfamily | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR050409 | Family | E3 ubiquitin-protein ligase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0000209 | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |