Gene detail

Detailed information of BRAKERLUSP00000022674.1 in Blastomussa wellsi

Genomic Location: chr5:2443967...2448941
NR annotation: XP_029211734.2, heat shock protein HSP 90-alpha-like [Acropora millepora]
Species Blastomussa wellsi · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERLUST00000022674

ATGCCTGAAATCGAAGAAGTACAGCAAATGGAAGAAGATTCCGAAGCGGAGACCTTTGCTTTCCAAGCGGAGATCGCTCAGTTGATGAGTTTGATCATCAACACATTTTACTCGAACAAGGAAATTTTCTTGCGAGAAATCATCTCAAACTCTTCGGATGCACTCGACAAGATTCGCTACCAAAGTTTGACAGACCCGACAAAACTTGACAGCTGCAAAGATCTGAAGATCGAACTTATCCCCAATAAAGATGACAATACTCTGACAATCATCGATACCGGGATTGGTATGACCAAGGCTGATCTCGTCAACAACTTGGGAACCATCGCTAAGAGTGGAACAAAGCAATTTATGGAAGCACTGCAGGCTGGTGCAGACATCTCcatgattggtcagtttggTGTGGGTTTCTACTCTGCCTATTTGGTTGCTGAGAAGGTTGAAGTTTACACCAAGCACAATGACGATGAGCATTACATCTGGCAATCTGCTGCAGGAGGGTCCTTCACTGTTCGCCGCCTTTCGGAGGAGGTGTTGTCCCGAGGAACAAAAATTGTTCTTCACCTCAAGGAAGACCAGGCAGAGTATTTAGAGGAGAGGCGTATCAAGGAGATTGTAAAAAAGCACAGCCAGTTCATTGGTTATCCAATTTCTCTTTTGGTGCAGAAGGAGCGAGACAAGGAGGTTAGtgacgatgaagatgaggaggatgaagaaaagaaagacaaagatgAGGACGAGAACAAAGATGATGAAGAGAGTGACAAGCCTAAGATAGAAGACCTTGACGAGGAAGATGAAGAAAAGAagaaggagaaaaagaaaaagaaaatcaaggAGAAGTATTCGGAACTGGAAGAGCTCAACAAGACAAAACCGCTATGGATGCGCAACACTGATGAAATCACAACAGAGGAATATGGTGAGTTCTACAAGAGCCTGACCAATGACTGGGAAGAACATTTGGCTGTCAAGCATTTCTCAGTTGAAGGGCAATTGGAGTTCCGTGCACTTCTGTTTCTTCCACGGAGGGCGCCATTTGATCTGTTTGAGAACAGGAAAAAGCGCAACAACATCAAGCTGTATGTGCGTCGCGTGTTCATCATGGACAATTGTGAGGATATAATTCCAGAGTACCTTAACTTTATTAAGGGCGTTGTAGATTCTGAAGATCTGCCGTTGAACATTTCTCGTGAAATGCTACAGCAGAACAAAATTTTGAAAGTGATCAGGAAAAACCTTGTCAAGAAGTGTTTGGAGCTGTTTGCTGAAGTTACAGAAGACAAGGACAACTACAAGAAGTTTTATGAGCAGTTTGGCAAGAACATGAAGCTTGGTATTCATGAAGACAGTGTCAACCGCACCAAACTTGCCGATCTTCTGAGATATCACTCTTCTGCCTCGGGCGACGAGATGACATCGTTGAAAGATTACGTGACACGTATGAAGGAGAACCAGAAGGATATCTACTACATTACTGGAGAGAACAAAGATCAGGTCGCACACTCTGCTTTTGTGGAGCGAGTTAAGAGCCGTGGTTTCGAGGTTTTGTACATGACGGAACCTATTGATGAGTACGCCGTTCAGCAGCTGAAGGAGTATGATGGTAAGAAACTTGTCAGTGTTACCAAGGAAGGACTTGAGCTTCCCGAGGATGATGAAGACAAAAAGAAGTGGGAAGAAAAGAAAGCGAAATTTGAGCCTCTCTGCAAGACAATCAAGGAAATCCTAGACAAGAAGGTGGAGAAGGTGGTTGTGTCATCTCGTCTGGTGTCGTCACCTTGCTGCATTGTGACCAGTCAGTTCGGTTGGACTGCTAACATGGAGCGAATCATGAAAGCACAGGCTCTGCGTGACAACAGTACGCTTGGATACATGGCAGCCAAGAAGCACCTTGAGGTGAATCCAGATCACTCGATTGTCGAGACCCTGAGACAAAAGGTGGAGGCTGATAAGAATGACAAGTCGGTGAAAGATCTTGTTATGTTGCTGTATGAAACATCTCTGTTGTCGTCTGGCTTCACCTTGGATGACCCTCAGGTTCATGCCGGTCGCATCTACAGGATGATCAGTTTGGGGCTTGGAATTGATGAAGATATGGAAGGTGAAGGAGCTGCAGCAGAGGCCAGCACTGAGGACATGCCACCCCTTGAAGGAGAAGATGGAGATGATGCCTCCAAGATGGAAGAAGTTGATTAA

Transcript

BRAKERLUST00000022674

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O57521	Heat shock protein HSP 90-beta OS=Danio rerio OX=7955 GN=hsp90ab1 PE=1 SV=2
P11501	Heat shock protein HSP 90-alpha OS=Gallus gallus OX=9031 GN=HSP90AA1 PE=3 SV=3
Q76LV2	Heat shock protein HSP 90-alpha OS=Bos taurus OX=9913 GN=HSP90AA1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001818 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13589 all species →	HATPase_c_3	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	Domain	Interproscan
PF00183 all species →	HSP90	Hsp90 protein	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003594 all species →	Domain	Histidine kinase/HSP90-like ATPase	Interproscan
IPR001404 all species →	Family	Heat shock protein Hsp90 family	Interproscan
IPR019805 all species →	Conserved_site	Heat shock protein Hsp90, conserved site	Interproscan
IPR037196 all species →	Homologous_superfamily	HSP90, C-terminal domain	Interproscan
IPR036890 all species →	Homologous_superfamily	Histidine kinase/HSP90-like ATPase superfamily	Interproscan
IPR020575 all species →	Domain	Heat shock protein Hsp90, N-terminal	Interproscan
IPR020568 all species →	Homologous_superfamily	Ribosomal protein uS5 domain 2-type superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11528 all species →	HEAT SHOCK PROTEIN 90 FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006457 all species →	Biological Process	protein folding	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0051082 all species →	Molecular Function	unfolded protein binding	Interproscan
GO:0140662 all species →	Molecular Function	ATP-dependent protein folding chaperone	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0032991 all species →	Cellular Component	protein-containing complex	Interproscan
GO:0034605 all species →	Biological Process	cellular response to heat	Interproscan
GO:0048471 all species →	Cellular Component	perinuclear region of cytoplasm	Interproscan
GO:0050821 all species →	Biological Process	protein stabilization	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04079	HSP90A, htpG; molecular chaperone HtpG	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Blastomussa wellsi tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Blastomussa wellsi, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →