Gene detail

Detailed information of BRAKERXEIP00000022398.1 in Muricea muricata

Genomic Location: chr10:13527641...13537208
NR annotation: CAB3988016.1, Rab3 GTPase-activating catalytic subunit [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERXEIT00000022398

ATGGCGGACGCCGAGGAGGACGAGAGTGAGTCAACAGTGTTTGAAATTACTGATTTTACAACTGCGTCTGAATGGGAAAGGTTTGTTTCACAAATTGAAGAAATTCTTCACAAATGGAAGCTTGACAATAGCAACAAAAAACCGTCATTTCTACAGCGTGTACGCAACTTCTCATCATCATCAAATAAAGATGAAAAGACTGGAAACTTGAAACCAATACCAAagaaaatgagctctgagACCAACGAATCATGTTGGGAGACATCACCAGAGACACTTCATTTTGCAGACTTTTGCTTTGATATTACCTACCACTGTTTGACAGGGAAGAATGGAACTAGGGAGGAACTCTCAGGGTTTGAAGATGGTCTTCCTTCTGGTGTCCTGGACATGTTTGACATGGATTATGATTTCCCACCAAGAGCTCACTGCCTCAGTCGATGGTATGGCTTGAAAGAGTTCTTGGTCTTATCACCATCAGTTGAGAATGCTGCCATCACAAGTGAGTCAAGGTGTCATTTGCTCCTCAGTTCTATCTCAATGGCTTTAGCGAATTCCAAGTGTTATGTTCCATTGCTGGTACAGTTACATCAGAAGTGGAGACGACTGTATCGTGGGCTCTGCTTGGGCAGTGGTTTCCGCACGTTATTTGAAATGGCTCAATTGCGTCATACTCCAAAGCAATTCAATCATCTTAAGGGCTTGTTGGATGTCTTTAAAGATAAACTGGCTCTCCGTGGGGCAAGCTGCCCGCCAATTACAATCACTGTAAGATTTACCTACTTCTTAAATGAATGGAGTGATACAGTTTGGCCCCAGGCTCCACCTGACGTTGACTCGTGTCTGGGAGATGAAGTGGGTTTATCAGATATCGCTACGTTGCCATTTGGTACGGGACAAGATGCCATCAGTGAGCTGCATTTGTCAGTGACTTGGCCGTGTTTGTCGGAAGATGTGATTGTGGACAATGGAATTTATTCTGATTTAGATCCGATCCAAGCACCGCAGTGGCATGTGAGAGTGAGAATGAATGATGACCCAAACTGTCTTTTAAGTGAATATATTGATTGTTATTTGAACCTATGTCATCGAAAAGATGCGACGTCAGTGAAGCACGATGCTTTATATGATGAGCCTGAAGATGCAAGCAAACACTTTGCTCAGGCATTTCAAAAACTCACCAAACCTGCTATTCCTTCCAACATACAGTCTGTTGTTAACAAGGCGACGTCAAGGATTACTGGCACAAATAGTGATGAGTCTCCAATACCAGCTCAACTGCTCGATAATATATTAAAGCATTTGTTTCCCGATGCTGATGTGGACCCAGATGATATTGCTGTGAAACAAGAAGAAatattgaagtcaaatatatATTCAACGAGAGATATTCCAATCGACAGATTTCGCGGCCTAAAAGGAGCTCCAGAAGATTGCCTGACTTACGTTTTGGCGATATGTCTTTGTATTGTAAATCACAGTTACGGAGGGTTACGAGCTGTGGCTTATCTTTGGCAAGAGTTTGTGTTGGAGATGCGATATCGCTGGGATCATGGAATTTTCATATCAAGACTTGCGTTGCAGGCCCCGAACCTTGATTGCTGTTTAATTCATCAGAAACTTCAGATGTTAAATTACTGCATAGCTCGAAAGTGTATGTCAAAGCGAAGTGAGACAAACATTAACCAAGAACAATCTGATAAACCACCTGGGAATCTAGAGCGAGCATCCAGTGCGAGATGTAGCTCTCCCGGTGATGACAGCAGTGAAGATGAATTTTTCGAAGCACTAGAAGATCAAGAGGATTCAGAAGATTCCTGTGGGGATGTTGAAGGAACTTCAAGGATGGCAGAGGGTAACATGAAACGAGAGGGAGCTTTGAAACGATGTGGGGATCTTAAGCTGTTGGTATCCGGTGAACCATTGTATATTCCAGTGACCCAGGAACCCGCTCCAATGACAGAAGACATGTTACAAGCACATGCTGACCTTCTTACACAACTGGGTACCACCGAGGAAGGCGCGAGGATTCGTGCCCAAATGCAAAGCGCTTCTTTGCTTTCCGACATGGAAGCGTTCAAGGCTGCCAACCCAGGCTGTCTATTAGAAGATTTCGTGCGGTGGTACTCGCCGAACGACTGGCTACAAGGAGAAGAGAGCGAGGAGGAGATTAAATATAGAAGAGAACTAGAACAAAAACAGAATGAGAAAAAGCAGAACCGGAGCGAGGAATGGAAGGtagatgatgatgaagaaatCACTGAAAACGAATTAAATGAAGCTTTTTGTGAAGCAAATAAAATGAATGAAGATTTACCTAGCAATCCTTCTTCAAAGGACTGGTGTGACGAGGGACGATTAAGCCTGCGCATGCGTGTCCAGGGAAATGTTTGGGAAGATAACTGGAACAATGCAAGAGCTCGTCCTGTGCGACGTCAGAAACGATTGTTTGATGAAACCAAAGAGGCTGAGAAGGTTCTTCATTATTTATCTGGATTACGACCAGCTGAAGTTGCCAGTGAACTCATCTCTATTGTGCTTCAAGCCTCGATAAGACGCATTGAGAACGCAGCCAGCAGCGATGCAGTTCGTTCCAGTGCTAACATTGAGCGCATCATAAGGAGAGCAAGTCGAGTGTTTCAAACGTCAGAAGAAAAGTTGACTTTGTACAATgaattgtttcaacaacttcGTAGTATTGAATTAAAGATTGCGCGTGCGCACTCATTGAAGATGAAACTACGAACATCTGAAGCGAAGAAATCAGACATTGACACCGAGGCTTTCGTTGCCTCGTTACTGGAGAAACCCGAAGTGAACGTCGTCGGAGCAAGTCGTGGACCTATGGGTCATGTGATTAAGGAGTTGTTCTCCAAACAAGAGATGATAAGATCGCAAGAGGAAGATTATGATAATCATGAAATTGTAAAGAAACCTGTTTTCAACCAATCACGACCTTTTCCTGCTCCCGCTGGACGTGAATTCATCTTACGAACAATAGCAAACTATCCGGGCAAGAGCTCCAGACAGTGCCCTCAGCGGATGTACTGTGTCCTAGTTGGGGAGGAATTCCGTATGGCGGCCGCGTTCACCTCCGATACTACATTCACGTAA

Transcript

BRAKERXEIT00000022398

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q80UJ7	Rab3 GTPase-activating protein catalytic subunit OS=Mus musculus OX=10090 GN=Rab3gap1 PE=1 SV=4
Q15042	Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP1 PE=1 SV=3
Q642R9	Rab3 GTPase-activating protein catalytic subunit OS=Xenopus laevis OX=8355 GN=rab3gap1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003186 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF19533 all species →	Rab3-GAP_cat_C	Rab3 GTPase-activating protein catalytic subunit C-terminal	Domain	Interproscan
PF13890 all species →	Rab3-GTPase_cat	Rab3 GTPase-activating protein catalytic subunit	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045700 all species →	Family	Rab3GAP catalytic subunit	Interproscan
IPR045698 all species →	Domain	Rab3GAP catalytic subunit, C-terminal	Interproscan
IPR026147 all species →	Domain	Rab3GAP catalytic subunit, conserved domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR21422 all species →	RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K18270	RAB3GAP1; Rab3 GTPase-activating protein catalytic subunit	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →