Gene detail

Detailed information of BRAKERXEIP00000023548.1 in Muricea muricata

Genomic Location: chr11:2098050...2120825
NR annotation: XP_028405043.1, disks large homolog 5-like isoform X1 [Dendronephthya gigantea]
Species Muricea muricata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

BRAKERXEIT00000023548

ATGGAAGAAGACTATAAAAGAATTTTAGATCGTCACCGTGACAAATTCAGACAAGCGGTGAACATCGAGCGGCTTAGTTCGTCTCTCCTCATAAGTCACATCCTAAGCGAAGCGGATTGGCAAATTATCGAGGCAGAAATCGGTAGTCAAAGGGTCGATCGGCTCCTGGATTTGCTCAAGACCAAAGGCTATGATAAATTCAAGCGTTTCTGCGTCATTCTAGAGACCACATACCCTTACATGCTTAACTGTATGTTCTTAGGGATGGACCCACCTAAGGACTTGTACTCAGgttcagGCCGGatttctaaaagcaaatcaAAGCATTCCGATCGTGACAAAGAGAATGGCCAAGGTGGCCCAAAACAAGGAAATGTTCATCGAAGTGTGAGCATGATTGAACATGACTCTTGCAAAGAGACAACATCCTTGAAAACAGAGCTGCGAGTAATTCAGAGGAAGTATGACAGTGTTGTTAAGAAGTTGAAGAAAATGGAACAAGAACGGGCAGAAGAATTAGCGAATGTTGACGATAATGGAAAAGAAGAAGGAGCTGAGGAGAAGGAATGGGAATGTGAGGCTATAAAACAGAAATATGAAGACATTGTCAAAGAAATCGAACTCTACCGCAAAGAAGCCGACGAACTGGCGGTAAAATGCAGCAGCCACGTCCAGGAATCCGAACACTTTCGAAACCTGCACTTGGTCGGCTTAAACAAGTGCGACCAGCTTGTCCGAGAGGCTCAAATGCTGAACCAAAAACTGAACGCGAGCGAAAAAGAGCGGGACAAATTGAAACAGGACTACGAGGAGATTATCCTCCTTCGAGAGCAGGAGAAAAAAGAAATAAGCGAGCTGCGAGGCAAGCGTCCTGCTGTTTGGAAACCGGAGGCAGGCGAGGACGGTAACGAGAACTTGCAAGCGATGAGCGACAAACTCGCTCTGGAACTGCAAATGAACGTCGAGAAGTACGGAGCTTTGGAAAGCAAGTTTGGAGAGTTACGGAAGAAGTTAGCCGAAGTGAACATGGAGTTGGAAAGCGCGCAAAACGAGAGGGCGTATTTAAAACGGCAGTTTGCCGTGACCAAACGTAATTTGGATAAATATATGCACGAGAATGAGATCGCGATGGGACGAGTTCATCAGGCTGAACAACACCGCGATGCTGCTGTGAAAGAAACTGATCAGGCGCTTGCATTGCAGCTCAAGGCAACGCGGGAACTCACCAAAATCAAGGAGGAGCGAAACAGTGCGCTTAGTGAATACAGGCTGGTGATGAGCGAGCGAGATAGCGTACACAAAGAAATGGATAAACTACAGGAGGACCTTGTCAAGGCACAGGAGGATGCCGGGAAACGGAAAGAGGAAGCAGAAAGACTAGGAGAAGAAAAGGAAATAGCCAATCACGATTTGAACATCGTCAAAAGCGAGCGGGATAAGGCAATGAAAGAATTGTATCTCGTCAAGCAGCGCATGAAACAACTGATGGCCGACATGGACGAAGTCAAGAGGGATCGTGAGAAGGCTCGAGAAGATGCCGATATGTTCCGAGAAGAGCGCGACGCTTCCCGACGTGAACGGCACGAGGCGATTATCCACCGAGACAAAATCCTGCGGGAGTGTTTCGAGGCTAAGCAGCGCAACGAGACGTTTAAAGGCGACAGCAAAGAGAGCGAAACTTTGAGGAAGCAATTCGATGCTTTGTCGAAAGAGCTTGCGAATGCGCTTAGCGAAGCTGAGGTTTCCAAGAAACGACGAGATTGGTCCTTCAGCGAGCGAGATAAAATGGTCAAGgaAAGAGACGCGTCCAAGGCAGCGTGTGACGTGTTGAGACAAGAGCGCGATCGGGCAGTGAGCGATCTCGCCGCATTGCTCAGGGATACGGATGAGATCAGACGAGAGCAAACCAAGTCTATGGAAGAAATGAAAACGCTTCGAGAGAGAATCAAGTTCAGACTCGATAGTGATGACCGCACAGAGGTGGTGACAAGTATGGATTCCGCCATTGATACCGACTCATGCACGGATTGGGAAACGGAGATGGTGGCCCTTGAAAAGagaagcgccaaggaGAAACTTGGTTTCGATGTGGCCGCCAGTAAATCTAGCATCGTTGTCACCAATGTTGTCAAAGACAGCGTGGCGTACGGCAAGCTAAGAGTGAACGATTGTTTGCTTCGTGTCAATAACGTCGAGGTTTCTACTATGAAATACGAGAAAGCTATTGAAGCGATAAACGAAGGAGATAGTCTGAATATTACGGTGAAGAGACGAAAACCTCTGAATGAAAAACGCTATTCATCTCCATTACACCTCACCGTCCCACATGGAAAAGaGCTGGGAATCTTAATCGACGACAATAAGACTGTCAGTTGGATAAAACCCGGAAGTGTTGCTGACTTGGAAGAGAGGCTGACCGTTGGTGATAAAATCATTACCGTCAACGGTACAGCGGTCACCACGCTCTCTCAAGCCGAAACCGAAGATCTTCTGAGCTCGAATATCCTCGCGCTCGAAGTCCAGAACCCCGTCGCATCGCCCCGAGTCAGTCCGCTCGAATCCCTTCTTGTCGAGGTCGACGACAAAATCATAAGGGACTCGACTATTCGCCAAAAGGCGGAATTCAAAGAGGCCAAGCTGGCGGACAGTCTGTCTGCTTTGCAAGGCTCGGAAAAGATCGGAACGAGCGACCTGTCCAGCGCTTTACATTCGGAGTTGGACGACGACAACTCGTCGATTTTCGTTCCAGATACGGCGCTAAATATGTCGCCATCGCTTACACCGCTGTACGAAGATAAAGAACGGACCAGGGGCACACAAACAGATACAGGTGCTCCCGAACTCGTCACACGCCGGTGTATGTCGGTATCGGAAAGATCCGATGCCTTGCCGAACGCTGCGATGACGGCTCAAAATCGGGCAATGTCCGTTGGAGTCTCGTCAACCTACGCCAGACGTCGGATGACGTCGGCAGTCGTTGCCAATACCGCGGAGGACGATCAAGTGACGTCACTAGATCTTGGTGTGCGATTTCCCGCCTCGAAGAAGAAAGCGATCCGACCGAAATCTGCTCCAGTTGTACGACCAGAGACTTTAGAGATGTTTATGGACACTAATCGTGTTATCCATTCAGGCGACACAACATTACCCCGTAGAACCCTGGTGCATCCACCTATATCCCCTTCCGACCCGCTGTCCCTGTCCGCACGAGCTAACCATCTCTCGGGAAGACCTCAAGCCATCTCACCGCCAGCTTTCAGTTCTCTATACAAGCCACGAACTGTCACCCATTTCGCCACACACAGCAGAAGTGCCCAGTCCTTTCCCTCGGTAAGCGAGGTGGGTATCCCAGGAGCCTCTACTACGCCGAATAACATGTCGCATTCATCCCTCCCGGAGGAGCCCGACACCGACCGATCGGTATCCGACGTACGACTACGAACGTGGACCGAACCACCTAAAAATCTACGCAGTCAAGAGAGTTACATCACAAGCACGACACCGCTGACTTTGCCGAAATCATCGAAAGACTCCGGTCGTTCCAGCCTCCCACGGCGTCGCCGCGTCAAATCCTCCTCATCTCATAGCCAGTCCTATAATACAATCGATACACACTCGACCATTTCAAGTCACTCCAGTTGCGGACCGAGCTCAGTGGGCTCGTCATCTGGACGCAACACTCCGCATGTGGTGACGCCTTCAACGCCATCTTTTGCGCGGGAAATAACGCCAGTCATTCGTATCAATCAACAACAACCCGATAATGGCGAAAAAAATGCAGAGAAAGTGCGAAAGCTCCACATCGAGAAAAGTTCCTACCCCCTCGGCATTCAGATCTCGCAAGGGAGTTCCGGTGGTATCTTTGTTACCACCGTGACGGAAGGAAGTATAGCGCAGAAGGCCGGGTTACGTTATGGAGATCAAATATTGGAGTTTAACGGAATCAACTTTCGGTCTGCCACTTACGATCAAGCCGCAATTATATTAAGTCAAGCAGAAGGCAGTGTTCGTCTCATGGTCCAGTATAATCCACAAAAACTGAAAGAGAATGTCATCGATAGTTTAACGAGTCATAATTCTTCCCAAGCAAGCATCCGAGTCGGCGATAGCGACATAACTCCTCCAGTTCCAAGACGTTTCGTTCCGACAAATGACGTAGAAGCTCCAAGTGAACCACGGTATATCACGACCGACCAGACTGTGCAGGGACTGGGACTGAACATTTTGGGCGGAAATGCGACGGGAATTTTTGTGTGTGACGTCAAATCGCCCGGACATGATCTTGGGATTAGGACTGGTGACCAAATACTCGAGTTTAACGGTTTCGATTTCACCGCCGTGACCCTGGAACAAGCCACGCTGGAATTGTGTAAACCGTCAGAGAAGATAACGATGAGAATGCAATACAACCCAGCAAAGTACAACGTTATAAAAGACCACCCAGGTGATTCCCTTTACGTCAGGGCAATGTTTGACCATCCAGCAACAAGCAAGGATCAGTTGTCTTTCAAGAAAGACGACATATTGTATATAACGGATACGCTGTACAATGGTCACGTGGGAAGTTGGAAAGCGTGGATTGTAAACAAGGAAGATGCACAACAACGGGAGTGTGGAATGATCCCGTCTCGAATGAAAGCCGATCAAATTGTGCTGTTACGACTGAGCGTCGCGCACGGAGATCCGGATCACAAATTGGCTGGCAGGCGGAGCTTCTTTAGACGCAGTAAAAAGGGAAGTCACAGCTACAGTGTCAGCCATTCGAGAGAGAGCAGCGACACCAGTGTTTCTACGTTTACAGAACTGGGTGCTGCTTCGTACCAGAATGTTGAAAGATTAGACACTCACCATCCACGACCTGTGATTATCTTGGGTGCCCTGGCTGATGTCGTCAGCAAGAAGCTGGCCACAGGGGCTCCGTACAAGTTCACACTTTGTCATAACCAACTTGTGTCAGCttcagaagttgaaattaaGAAGGCCGTCGCAGATGGCGTCTATCTGGATTACGTCGTCAAAGATGGACAATTTTATGTCACATTTATGTCAACGGTCAGGGAAGATATGGACAAGTTGAAACACAGCATCCTTGAAGTATCACCGCTGGCCATCGAGAAGCTTCGTGCACAGCGCATTTATCCCATCGTTTTATTCGTGAAATACAAATCAGCCAAACATATCAAAGAGCAAAGAGACACGAAGCACTTGCAGCAGAAAGTGTCCACAAAAGACGCGAGATCAATGTATGAAAACTGTGCGAGGATTGAGCACGAATTTCGGTCGGAATTCACTGCTGTTATTCCTGGAGCGAGTATCAACTCGCTGTTCTCGCAAATTCAAGATATTGTTGATGAACATCAAAAGAAGACATTGTGGATTCCTATGACATCaaattaa

Transcript

BRAKERXEIT00000023548

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8TDM6	Disks large homolog 5 OS=Homo sapiens OX=9606 GN=DLG5 PE=1 SV=4
E9Q9R9	Disks large homolog 5 OS=Mus musculus OX=10090 GN=Dlg5 PE=1 SV=1
Q12959	Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003781 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan
PF00625 all species →	Guanylate_kin	Guanylate kinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR001315 all species →	Domain	CARD domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan
IPR053004 all species →	Family	MAGUK Family Regulators of Signaling Pathways	Interproscan
IPR035537 all species →	Domain	Disks large homologue 5, SH3 domain	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR008145 all species →	Domain	Guanylate kinase/L-type calcium channel beta subunit	Interproscan
IPR011029 all species →	Homologous_superfamily	Death-like domain superfamily	Interproscan
IPR008144 all species →	Domain	Guanylate kinase-like domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46360 all species →	DISKS LARGE HOMOLOG 5	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0042981 all species →	Biological Process	regulation of apoptotic process	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0035331 all species →	Biological Process	negative regulation of hippo signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K24050	DLG5; discs large protein 5	-	Hippo signaling pathway - fly	ko04391	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →