Genomic Location: chr11:288159...313128
NR annotation: CAB3992156.1, E3 ubiquitin- ligase UBR5 isoform X2 [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families
| CDS |
| BRAKERXEIT00000024459 |
| Transcript |
| BRAKERXEIT00000024459 |
| Protein |
| BRAKERXEIP00000024459.1 |
| UniProt accession | Description |
|---|---|
| Q80TP3 | E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2 |
| O95071 | E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 |
| Q62671 | E3 ubiquitin-protein ligase UBR5 OS=Rattus norvegicus OX=10116 GN=Ubr5 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002341 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity|HECT · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 activity|UBR-box · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 all species → | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00658 all species → | PABP | Poly-adenylate binding protein, unique domain | Family | Interproscan |
| PF11547 all species → | E3_UbLigase_EDD | E3 ubiquitin ligase EDD | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR009091 all species → | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR000569 all species → | Domain | HECT domain | Interproscan |
| IPR035983 all species → | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR002004 all species → | Domain | Polyadenylate-binding protein/Hyperplastic disc protein | Interproscan |
| IPR024725 all species → | Domain | E3 ubiquitin-protein ligase UBR5, ubiquitin-associated domain | Interproscan |
| IPR047503 all species → | Domain | E3 ubiquitin-protein ligase UBR5, UBR-box | Interproscan |
| IPR003126 all species → | Domain | Zinc finger, UBR-type | Interproscan |
| IPR036053 all species → | Homologous_superfamily | PABC (PABP) domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46276 all species → | E3 UBIQUITIN-PROTEIN LIGASE UBR5 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000209 all species → | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0034450 all species → | Molecular Function | ubiquitin-ubiquitin ligase activity | Interproscan |
| GO:0090263 all species → | Biological Process | positive regulation of canonical Wnt signaling pathway | Interproscan |
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10593 | EDD1, UBR5; E3 ubiquitin-protein ligase EDD1 | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |