Detailed information of BRAKERXEIP00000024459.1 in Muricea muricata

Genomic Location: chr11:288159...313128
NR annotation: CAB3992156.1, E3 ubiquitin- ligase UBR5 isoform X2 [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q80TP3E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2
O95071E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2
Q62671E3 ubiquitin-protein ligase UBR5 OS=Rattus norvegicus OX=10116 GN=Ubr5 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002341 (this species only) · gene tree & orthology
Ubiquitin familyE3|E3 activity|HECT · all ubiquitin genes in this species
Ubiquitin familyE3|E3 activity|UBR-box · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00632
all species →
HECTHECT-domain (ubiquitin-transferase)DomainInterproscan
PF00658
all species →
PABPPoly-adenylate binding protein, unique domainFamilyInterproscan
PF11547
all species →
E3_UbLigase_EDDE3 ubiquitin ligase EDDDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR009091
all species →
Homologous_superfamilyRegulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIInterproscan
IPR000569
all species →
DomainHECT domainInterproscan
IPR035983
all species →
Homologous_superfamilyHECT, E3 ligase catalytic domainInterproscan
IPR002004
all species →
DomainPolyadenylate-binding protein/Hyperplastic disc proteinInterproscan
IPR024725
all species →
DomainE3 ubiquitin-protein ligase UBR5, ubiquitin-associated domainInterproscan
IPR047503
all species →
DomainE3 ubiquitin-protein ligase UBR5, UBR-boxInterproscan
IPR003126
all species →
DomainZinc finger, UBR-typeInterproscan
IPR036053
all species →
Homologous_superfamilyPABC (PABP) domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46276
all species →
E3 UBIQUITIN-PROTEIN LIGASE UBR5Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000209
all species →
Biological Processprotein polyubiquitinationInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0034450
all species →
Molecular Functionubiquitin-ubiquitin ligase activityInterproscan
GO:0090263
all species →
Biological Processpositive regulation of canonical Wnt signaling pathwayInterproscan
GO:0004842
all species →
Molecular Functionubiquitin-protein transferase activityInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0043130
all species →
Molecular Functionubiquitin bindingInterproscan
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10593EDD1, UBR5; E3 ubiquitin-protein ligase EDD1EC:2.3.2.26
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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