Genomic Location: chr16:10331709...10336544
NR annotation: CAB3989676.1, Isovaleryl- dehydrogenase, mitochondrial [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families
| CDS |
| BRAKERXEIT00000029437 |
| Transcript |
| BRAKERXEIT00000029437 |
| Protein |
| BRAKERXEIP00000029437.1 |
| UniProt accession | Description |
|---|---|
| Q5RBD5 | Isovaleryl-CoA dehydrogenase, mitochondrial OS=Pongo abelii OX=9601 GN=IVD PE=2 SV=1 |
| P26440 | Isovaleryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=IVD PE=1 SV=2 |
| P12007 | Isovaleryl-CoA dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Ivd PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004612 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00441 all species → | Acyl-CoA_dh_1 | Acyl-CoA dehydrogenase, C-terminal domain | Domain | Interproscan |
| PF02771 all species → | Acyl-CoA_dh_N | Acyl-CoA dehydrogenase, N-terminal domain | Domain | Interproscan |
| PF02770 all species → | Acyl-CoA_dh_M | Acyl-CoA dehydrogenase, middle domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036250 all species → | Homologous_superfamily | Acyl-CoA dehydrogenase-like, C-terminal | Interproscan |
| IPR037069 all species → | Homologous_superfamily | Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily | Interproscan |
| IPR009075 all species → | Domain | Acyl-CoA dehydrogenase/oxidase, C-terminal | Interproscan |
| IPR013786 all species → | Domain | Acyl-CoA dehydrogenase/oxidase, N-terminal | Interproscan |
| IPR034183 all species → | Family | Isovaleryl-CoA dehydrogenase | Interproscan |
| IPR009100 all species → | Homologous_superfamily | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily | Interproscan |
| IPR006089 all species → | Conserved_site | Acyl-CoA dehydrogenase, conserved site | Interproscan |
| IPR046373 all species → | Homologous_superfamily | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily | Interproscan |
| IPR006091 all species → | Domain | Acyl-CoA oxidase/dehydrogenase, middle domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43884 all species → | ACYL-COA DEHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016627 all species → | Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors | Interproscan |
| GO:0050660 all species → | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0003995 all species → | Molecular Function | acyl-CoA dehydrogenase activity | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0006552 all species → | Biological Process | L-leucine catabolic process | Interproscan |
| GO:0008470 all species → | Molecular Function | 3-methylbutanoyl-CoA dehydrogenase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00253 | IVD, ivd; isovaleryl-CoA dehydrogenase | EC:1.3.8.4 | Valine, leucine and isoleucine degradation | ko00280 | deepkoala |
Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
