Detailed information of BRAKERXEIP00000044513.1 in Muricea muricata

Genomic Location: chr3:56099229...56111030
NR annotation: CAB4017205.1, ECT2 isoform X1 [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9H8V3Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4
Q07139Protein ECT2 OS=Mus musculus OX=10090 GN=Ect2 PE=1 SV=2
Q96PE2Rho guanine nucleotide exchange factor 17 OS=Homo sapiens OX=9606 GN=ARHGEF17 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004186 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF21242
all species →
ECT2_PHECT2, PH domainDomainInterproscan
PF00533
all species →
BRCTBRCA1 C Terminus (BRCT) domainFamilyInterproscan
PF12738
all species →
PTCB-BRCTtwin BRCT domainFamilyInterproscan
PF00621
all species →
RhoGEFRhoGEF domainDomainInterproscan
PF21243
all species →
ECT2_BRCT0ECT2, BRCT0 domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR049395
all species →
DomainECT2, PH domainInterproscan
IPR036420
all species →
Homologous_superfamilyBRCT domain superfamilyInterproscan
IPR000219
all species →
DomainDbl homology (DH) domainInterproscan
IPR001357
all species →
DomainBRCT domainInterproscan
IPR026817
all species →
FamilyGuanine nucleotide exchange factor Ect2Interproscan
IPR035899
all species →
Homologous_superfamilyDbl homology (DH) domain superfamilyInterproscan
IPR001331
all species →
Conserved_siteGuanine-nucleotide dissociation stimulator, CDC24, conserved siteInterproscan
IPR011993
all species →
Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR049396
all species →
DomainECT2, BRCT0 domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR16777
all species →
PROTEIN ECT2Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005085
all species →
Molecular Functionguanyl-nucleotide exchange factor activityInterproscan
GO:0000281
all species →
Biological Processmitotic cytokinesisInterproscan
GO:0005096
all species →
Molecular FunctionGTPase activator activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005938
all species →
Cellular Componentcell cortexInterproscan
GO:0007399
all species →
Biological Processnervous system developmentInterproscan
GO:0043547
all species →
Biological Processpositive regulation of GTPase activityInterproscan
GO:0090630
all species →
Biological Processactivation of GTPase activityInterproscan
GO:2000431
all species →
Biological Processregulation of cytokinesis, actomyosin contractile ring assemblyInterproscan
GO:0035556
all species →
Biological Processintracellular signal transductionInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K20704ECT2, ARHGEF31; protein ECT2-Membrane traffickingko04131deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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