Genomic Location: chr3:56099229...56111030
NR annotation: CAB4017205.1, ECT2 isoform X1 [Paramuricea clavata]
Species Muricea muricata · all data for this species · gene families
| CDS |
| BRAKERXEIT00000044513 |
| Transcript |
| BRAKERXEIT00000044513 |
| Protein |
| BRAKERXEIP00000044513.1 |
| UniProt accession | Description |
|---|---|
| Q9H8V3 | Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 |
| Q07139 | Protein ECT2 OS=Mus musculus OX=10090 GN=Ect2 PE=1 SV=2 |
| Q96PE2 | Rho guanine nucleotide exchange factor 17 OS=Homo sapiens OX=9606 GN=ARHGEF17 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004186 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21242 all species → | ECT2_PH | ECT2, PH domain | Domain | Interproscan |
| PF00533 all species → | BRCT | BRCA1 C Terminus (BRCT) domain | Family | Interproscan |
| PF12738 all species → | PTCB-BRCT | twin BRCT domain | Family | Interproscan |
| PF00621 all species → | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF21243 all species → | ECT2_BRCT0 | ECT2, BRCT0 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR049395 all species → | Domain | ECT2, PH domain | Interproscan |
| IPR036420 all species → | Homologous_superfamily | BRCT domain superfamily | Interproscan |
| IPR000219 all species → | Domain | Dbl homology (DH) domain | Interproscan |
| IPR001357 all species → | Domain | BRCT domain | Interproscan |
| IPR026817 all species → | Family | Guanine nucleotide exchange factor Ect2 | Interproscan |
| IPR035899 all species → | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR001331 all species → | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR049396 all species → | Domain | ECT2, BRCT0 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR16777 all species → | PROTEIN ECT2 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0000281 all species → | Biological Process | mitotic cytokinesis | Interproscan |
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005938 all species → | Cellular Component | cell cortex | Interproscan |
| GO:0007399 all species → | Biological Process | nervous system development | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
| GO:0090630 all species → | Biological Process | activation of GTPase activity | Interproscan |
| GO:2000431 all species → | Biological Process | regulation of cytokinesis, actomyosin contractile ring assembly | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K20704 | ECT2, ARHGEF31; protein ECT2 | - | Membrane trafficking | ko04131 | deepkoala |
Genes whose expression across the transcriptome samples of Muricea muricata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Muricea muricata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |